Serum H-Ferritin-To-Ferritin Ratio as a Biomarker of Hemophagocytic Lymphohistiocytosis in Critically Ill Patients With Hyperferritinemia.

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Title: Serum H-Ferritin-To-Ferritin Ratio as a Biomarker of Hemophagocytic Lymphohistiocytosis in Critically Ill Patients With Hyperferritinemia.
Authors: Debaugnies F; Laboratory of Translational Research, Centre Hospitalier Universitaire Brugmann, Université Libre de Bruxelles, Brussels, Belgium.; Medical Biology Department, Laboratoire National de Santé, Dudelange, Luxembourg.; Laboratory of Clinical Chemistry, Centre Hospitalier de Luxembourg, Luxembourg., Goetzinger F; Medical Biology Department, Laboratoire National de Santé, Dudelange, Luxembourg., Wolff F; Clinical Chemistry Department, LHUB-ULB, Université Libre de Bruxelles, Brussels, Belgium., Impens F; VIB-UGent Center for Medical Biotechnology, VIB, Ghent, Belgium.; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.; VIB Proteomics Core, VIB, Ghent, Belgium., Dufour S; VIB-UGent Center for Medical Biotechnology, VIB, Ghent, Belgium.; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.; VIB Proteomics Core, VIB, Ghent, Belgium., Van Haver D; VIB-UGent Center for Medical Biotechnology, VIB, Ghent, Belgium.; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.; VIB Proteomics Core, VIB, Ghent, Belgium., Gottignies P; Department of Intensive Care, Hôpitaux IRIS-Sud, Brussels, Belgium., La Schiazza R; Laboratory of Clinical Chemistry, Centre Hospitalier de Luxembourg, Luxembourg., Mahadeb B; Laboratory of Microbiology, Centre Hospitalier Universitaire Brugmann, Université Libre de Bruxelles, Brussels, Belgium., Meuleman N; Hematology Department, Jules Bordet Institute, Brussels, Belgium., Nagant C; Laboratory of Immunology, Centre Hospitalier Universitaire Brugmann, Université Libre de Bruxelles, Brussels, Belgium., Rozen L; Laboratory of Hematology, Centre Hospitalier Universitaire Brugmann, Université Libre de Bruxelles, Brussels, Belgium., Borde P; Medical Biology Department, Laboratoire National de Santé, Dudelange, Luxembourg., Corazza F; Laboratory of Translational Research, Centre Hospitalier Universitaire Brugmann, Université Libre de Bruxelles, Brussels, Belgium.; Laboratory of Immunology, Centre Hospitalier Universitaire Brugmann, Université Libre de Bruxelles, Brussels, Belgium.
Source: American journal of hematology [Am J Hematol] 2026 Mar; Vol. 101 (3), pp. 648-653. Date of Electronic Publication: 2026 Jan 06.
Publication Type: Letter
Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 7610369 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-8652 (Electronic) Linking ISSN: 03618609 NLM ISO Abbreviation: Am J Hematol Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
Description
ISSN:1096-8652
DOI:10.1002/ajh.70189