Drug and single-cell gene expression integration identifies sensitive and resistant glioblastoma cell populations.
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| Title: | Drug and single-cell gene expression integration identifies sensitive and resistant glioblastoma cell populations. |
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| Authors: | Suter RK; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA. RKS82@Georgetown.edu., Jermakowicz AM; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA., Veeramachaneni R; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA., D'Antuono M; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA., Zhang L; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA., Chowdary R; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA., Kaeppeli S; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA., Sharp M; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA., Palwai P; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA., Stathias V; Department of Molecular and Cellular Pharmacology, Institute for Data Science & Computing, University of Miami Miller School of Medicine, Miami, FL, USA.; Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA., Baker G; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA., Ruiz L; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA., Walters W; Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, USA., Cepero M; Department of Neurology, University of Miami Miller School of Medicine, Miami, FL, USA., Burgenske D; Department of Radiation Oncology, Mayo Clinic, Rochester, MN, USA., Reilly EB; AbbVie, Oncology Discovery, North Chicago, IL, USA., Oleksijew A; AbbVie, Oncology Discovery, North Chicago, IL, USA., Anderson MG; AbbVie, Oncology Discovery, North Chicago, IL, USA., Williams SL; Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.; Department of Neurology, University of Miami Miller School of Medicine, Miami, FL, USA., Ivan ME; Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.; Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, USA., Komotar RJ; Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.; Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, USA., De La Fuente MI; Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.; Department of Neurology, University of Miami Miller School of Medicine, Miami, FL, USA., Stein G; Curtana Pharmaceuticals, Inc., Austin, TX, USA., Wojcinski A; Pacific Neuroscience Institute and Saint John's Cancer Institute, Providence Health System, Santa Monica, CA, USA., Kesari S; Pacific Neuroscience Institute and Saint John's Cancer Institute, Providence Health System, Santa Monica, CA, USA.; Asthra Health and Lundquist Institute, Santa Monica, CA, USA., Sarkaria JN; Department of Radiation Oncology, Mayo Clinic, Rochester, MN, USA., Schürer SC; Department of Molecular and Cellular Pharmacology, Institute for Data Science & Computing, University of Miami Miller School of Medicine, Miami, FL, USA.; Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA., Ayad NG; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA. NA853@Georgetown.edu. |
| Source: | Nature communications [Nat Commun] 2026 Jan 07; Vol. 17 (1), pp. 99. Date of Electronic Publication: 2026 Jan 07. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-67783-5 |
