Diagnostic accuracy of combinatorial mRNA biomarkers for non-invasive detection and therapy monitoring of oral and oropharyngeal SCC.

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Title: Diagnostic accuracy of combinatorial mRNA biomarkers for non-invasive detection and therapy monitoring of oral and oropharyngeal SCC.
Authors: Hose L; Department of Otolaryngology, Head and Neck Surgery, Klinikum Bielefeld-Mitte, Medical School OWL, Bielefeld University, Bielefeld, Germany. leonie.hose@uni-bielefeld.de., Tekin AC; Department of Otolaryngology, Head and Neck Surgery, Klinikum Bielefeld-Mitte, Medical School OWL, Bielefeld University, Bielefeld, Germany., Verwaaijen B; Core Unit Laboratory Research at Department of Laboratory Medicine, Microbiology and Transfusion Medicine, Klinikum Bielefeld- Mitte, Bielefeld, Germany., Kim R; Department of Otolaryngology, Head and Neck Surgery, Klinikum Bielefeld-Mitte, Medical School OWL, Bielefeld University, Bielefeld, Germany., Rückert-Reed C; Medical School OWL, Bielefeld University, Bielefeld, Germany.; Center for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, Germany., Hamberger U; Department of Pathology, Klinikum Bielefeld-Mitte, Bielefeld, Germany., Busche T; Medical School OWL, Bielefeld University, Bielefeld, Germany.; Center for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, Germany., Scholtz LU; Department of Otolaryngology, Head and Neck Surgery, Klinikum Bielefeld-Mitte, Medical School OWL, Bielefeld University, Bielefeld, Germany., Brasch F; Department of Pathology, Klinikum Bielefeld-Mitte, Bielefeld, Germany., Todt I; Department of Otolaryngology, Head and Neck Surgery, Klinikum Bielefeld-Mitte, Medical School OWL, Bielefeld University, Bielefeld, Germany., Goon P; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Schürmann M; Department of Otolaryngology, Head and Neck Surgery, Klinikum Bielefeld-Mitte, Medical School OWL, Bielefeld University, Bielefeld, Germany.
Source: British journal of cancer [Br J Cancer] 2026 Mar; Vol. 134 (6), pp. 961-974. Date of Electronic Publication: 2026 Jan 08.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-1827 (Electronic) Linking ISSN: 00070920 NLM ISO Abbreviation: Br J Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1532-1827
DOI:10.1038/s41416-025-03313-w