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Proteasome inhibition by VR23 enhances autophagic clearance of FUSP525L-mediated persistent stress granule in SH-SY5Y cells.

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Title: Proteasome inhibition by VR23 enhances autophagic clearance of FUSP525L-mediated persistent stress granule in SH-SY5Y cells.
Authors: Kim SH; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, 80 Daehakro, Bukgu, Daegu, 41566, Republic of Korea., So JH; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, 80 Daehakro, Bukgu, Daegu, 41566, Republic of Korea., Kim YH; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, 80 Daehakro, Bukgu, Daegu, 41566, Republic of Korea., Kim HS; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, 80 Daehakro, Bukgu, Daegu, 41566, Republic of Korea., Park NY; Organelle Institute, Kyungpook National University, 80 Daehakro, Bukgu, Daegu, 41566, Republic of Korea., Kim JB; Organelle Institute, Kyungpook National University, 80 Daehakro, Bukgu, Daegu, 41566, Republic of Korea., Jo DS; Orgasis Corp., Suwon, Gyeonggi-do, Republic of Korea., Yeom E; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, 80 Daehakro, Bukgu, Daegu, 41566, Republic of Korea., Lee JA; Department of Biological Sciences and Biotechnology, College of Life Sciences and Nanotechnology, Hannam University, Daejeon, Republic of Korea., Bae JE; Organelle Institute, Kyungpook National University, 80 Daehakro, Bukgu, Daegu, 41566, Republic of Korea. jieunbae@knu.ac.kr., Cho DH; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, 80 Daehakro, Bukgu, Daegu, 41566, Republic of Korea. dhcho@knu.ac.kr.; Organelle Institute, Kyungpook National University, 80 Daehakro, Bukgu, Daegu, 41566, Republic of Korea. dhcho@knu.ac.kr.
Source: Molecular brain [Mol Brain] 2026 Jan 08; Vol. 19 (1), pp. 10. Date of Electronic Publication: 2026 Jan 08.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101468876 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-6606 (Electronic) Linking ISSN: 17566606 NLM ISO Abbreviation: Mol Brain Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Proteasome inhibition by VR23 enhances autophagic clearance of FUS<superscript>P525L</superscript>-mediated persistent stress granule in SH-SY5Y cells.
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  Data: <searchLink fieldCode="AU" term="%22Kim+SH%22">Kim SH</searchLink>; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, 80 Daehakro, Bukgu, Daegu, 41566, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22So+JH%22">So JH</searchLink>; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, 80 Daehakro, Bukgu, Daegu, 41566, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+YH%22">Kim YH</searchLink>; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, 80 Daehakro, Bukgu, Daegu, 41566, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+HS%22">Kim HS</searchLink>; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, 80 Daehakro, Bukgu, Daegu, 41566, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+NY%22">Park NY</searchLink>; Organelle Institute, Kyungpook National University, 80 Daehakro, Bukgu, Daegu, 41566, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JB%22">Kim JB</searchLink>; Organelle Institute, Kyungpook National University, 80 Daehakro, Bukgu, Daegu, 41566, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jo+DS%22">Jo DS</searchLink>; Orgasis Corp., Suwon, Gyeonggi-do, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yeom+E%22">Yeom E</searchLink>; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, 80 Daehakro, Bukgu, Daegu, 41566, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JA%22">Lee JA</searchLink>; Department of Biological Sciences and Biotechnology, College of Life Sciences and Nanotechnology, Hannam University, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Bae+JE%22">Bae JE</searchLink>; Organelle Institute, Kyungpook National University, 80 Daehakro, Bukgu, Daegu, 41566, Republic of Korea. jieunbae@knu.ac.kr.<br /><searchLink fieldCode="AU" term="%22Cho+DH%22">Cho DH</searchLink>; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, 80 Daehakro, Bukgu, Daegu, 41566, Republic of Korea. dhcho@knu.ac.kr.; Organelle Institute, Kyungpook National University, 80 Daehakro, Bukgu, Daegu, 41566, Republic of Korea. dhcho@knu.ac.kr.
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  Data: <searchLink fieldCode="JN" term="%22101468876%22">Molecular brain</searchLink> [Mol Brain] 2026 Jan 08; Vol. 19 (1), pp. 10. <i>Date of Electronic Publication: </i>2026 Jan 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101468876 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1756-6606 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217566606%22">17566606 </searchLink><i>NLM ISO Abbreviation: </i>Mol Brain <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s13041-025-01273-z
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        Text: English
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              M: 01
              Text: 2026 Jan 08
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