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NIPBL-mediated 3D genome folding translates enhancer priming into gene activation and safeguards lineage fidelity during embryonic transitions.

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Bibliographic Details
Title: NIPBL-mediated 3D genome folding translates enhancer priming into gene activation and safeguards lineage fidelity during embryonic transitions.
Authors: Ni Z; Structural Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Ma X; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Do SC; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Cheng L; Structural Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Glenn RA; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Vierbuchen T; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Pertsinidis A; Structural Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Dec 31. Date of Electronic Publication: 2025 Dec 31.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.64898/2025.12.30.686824