Combined creatine and β-hydroxy-β-methylbutyrate supplementation with integral conditioning exercise enhances functional performance and metabolic health in physically active older adults: A randomized controlled crossover trial.

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Title: Combined creatine and β-hydroxy-β-methylbutyrate supplementation with integral conditioning exercise enhances functional performance and metabolic health in physically active older adults: A randomized controlled crossover trial.
Authors: Ramos-Hernández R; Faculty of Health Sciences, University of Burgos (UBU), Burgos, 09001, Spain.; IAFIV Research Group, University of Burgos (UBU), Burgos, 09001, Spain., Busto N; Faculty of Health Sciences, University of Burgos (UBU), Burgos, 09001, Spain.; IAFIV Research Group, University of Burgos (UBU), Burgos, 09001, Spain., Miguel-Ortega Á; Faculty of Education, Alfonso X 'El Sabio' University (UAX), Madrid, 28691, Spain., Martínez-Ferrán M; Faculty of Health Sciences, University of Burgos (UBU), Burgos, 09001, Spain.; IAFIV Research Group, University of Burgos (UBU), Burgos, 09001, Spain.; Working Group on Nutrition for Exercise and Sport, Spanish Nutrition Society 'SEÑ', Madrid, 28010, Spain., Santamaría-Peláez M; Faculty of Health Sciences, University of Burgos (UBU), Burgos, 09001, Spain., Saiz-Rodríguez M; Faculty of Health Sciences, University of Burgos (UBU), Burgos, 09001, Spain.; IAFIV Research Group, University of Burgos (UBU), Burgos, 09001, Spain., Mielgo-Ayuso J; Faculty of Health Sciences, University of Burgos (UBU), Burgos, 09001, Spain. jfmielgo@ubu.es.; IAFIV Research Group, University of Burgos (UBU), Burgos, 09001, Spain. jfmielgo@ubu.es.; Working Group on Nutrition for Exercise and Sport, Spanish Nutrition Society 'SEÑ', Madrid, 28010, Spain. jfmielgo@ubu.es.
Source: Aging clinical and experimental research [Aging Clin Exp Res] 2026 Jan 09; Vol. 38 (1), pp. 44. Date of Electronic Publication: 2026 Jan 09.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 101132995 Publication Model: Electronic Cited Medium: Internet ISSN: 1720-8319 (Electronic) Linking ISSN: 15940667 NLM ISO Abbreviation: Aging Clin Exp Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1720-8319
DOI:10.1007/s40520-025-03312-0