Senolytic reduction of senescent cells mitigates atrial arrhythmia vulnerability in aging rabbits.

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Bibliographic Details
Title: Senolytic reduction of senescent cells mitigates atrial arrhythmia vulnerability in aging rabbits.
Authors: Sengun E; The Warren Alpert Medical School of Brown University, Providence, Rhode Island; Cardiovascular Research Center, Rhode Island Hospital, Providence, Rhode Island; Department of Pharmacology, Institute of Graduate Studies in Health Sciences, Istanbul University, Istanbul, Türkiye., Zhou L; The Warren Alpert Medical School of Brown University, Providence, Rhode Island; Cardiovascular Research Center, Rhode Island Hospital, Providence, Rhode Island., Kelsey M; Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island., Turan NN; The Warren Alpert Medical School of Brown University, Providence, Rhode Island; Cardiovascular Research Center, Rhode Island Hospital, Providence, Rhode Island; School of Nursing and Health Sciences, Providence College, Providence, Rhode Island., Lu Y; Cardiovascular Research Center, Rhode Island Hospital, Providence, Rhode Island., Kabakov AY; The Warren Alpert Medical School of Brown University, Providence, Rhode Island; Cardiovascular Research Center, Rhode Island Hospital, Providence, Rhode Island., Bronk P; The Warren Alpert Medical School of Brown University, Providence, Rhode Island; Cardiovascular Research Center, Rhode Island Hospital, Providence, Rhode Island., Mi E; The Warren Alpert Medical School of Brown University, Providence, Rhode Island; Cardiovascular Research Center, Rhode Island Hospital, Providence, Rhode Island., Kim TY; The Warren Alpert Medical School of Brown University, Providence, Rhode Island; Cardiovascular Research Center, Rhode Island Hospital, Providence, Rhode Island., Vijayakumar S; The Warren Alpert Medical School of Brown University, Providence, Rhode Island; Cardiovascular Research Center, Rhode Island Hospital, Providence, Rhode Island., Price D; The Warren Alpert Medical School of Brown University, Providence, Rhode Island; Cardiovascular Research Center, Rhode Island Hospital, Providence, Rhode Island., Nussbaum SS; The Warren Alpert Medical School of Brown University, Providence, Rhode Island; Cardiovascular Research Center, Rhode Island Hospital, Providence, Rhode Island., Song C; The Warren Alpert Medical School of Brown University, Providence, Rhode Island; Cardiovascular Research Center, Rhode Island Hospital, Providence, Rhode Island., Feng J; The Warren Alpert Medical School of Brown University, Providence, Rhode Island; Cardiovascular Research Center, Rhode Island Hospital, Providence, Rhode Island., Sellke FW; The Warren Alpert Medical School of Brown University, Providence, Rhode Island; Cardiovascular Research Center, Rhode Island Hospital, Providence, Rhode Island., Dubielecka-Szczerba P; The Warren Alpert Medical School of Brown University, Providence, Rhode Island; Department of Hematology & Oncology, Rhode Island Hospital, Providence, Rhode Island., Del Monte F; Medical University of South Carolina, Charleston, South Carolina., Nerbonne J; Department of Developmental Biology, Medical School of Washington University, St. Louis, Missouri., Uydes-Dogan BS; Department of Pharmacology, Faculty of Pharmacy, Istanbul University, Istanbul, Türkiye, and., Roder K; The Warren Alpert Medical School of Brown University, Providence, Rhode Island; Cardiovascular Research Center, Rhode Island Hospital, Providence, Rhode Island., Choi BR; The Warren Alpert Medical School of Brown University, Providence, Rhode Island; Cardiovascular Research Center, Rhode Island Hospital, Providence, Rhode Island., Van Wagoner DR; Department of Heart, Blood and Kidney Research, Cleveland Clinic, Cleveland, Ohio., Sedivy JM; Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island., Koren G; The Warren Alpert Medical School of Brown University, Providence, Rhode Island; Cardiovascular Research Center, Rhode Island Hospital, Providence, Rhode Island. Electronic address: gideon_koren@brown.edu.
Source: Heart rhythm [Heart Rhythm] 2026 Apr; Vol. 23 (4), pp. e675-e691. Date of Electronic Publication: 2026 Jan 07.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101200317 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1556-3871 (Electronic) Linking ISSN: 15475271 NLM ISO Abbreviation: Heart Rhythm Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1556-3871
DOI:10.1016/j.hrthm.2026.01.007