MSLN-mediated activation of EGFR-ERK1/2 signaling drives liver metastasis in breast cancer.

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Title: MSLN-mediated activation of EGFR-ERK1/2 signaling drives liver metastasis in breast cancer.
Authors: Chen J; Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Key Laboratory of Laboratory Medical Diagnostics, Chinese Ministry of Education, Chongqing Medical University, Chongqing, China., Lu Z; Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Key Laboratory of Laboratory Medical Diagnostics, Chinese Ministry of Education, Chongqing Medical University, Chongqing, China., Zhang G; Department of Breast Surgery, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, China., Meng D; Key Laboratory of Laboratory Medical Diagnostics, Chinese Ministry of Education, Chongqing Medical University, Chongqing, China., Chang C; Key Laboratory of Laboratory Medical Diagnostics, Chinese Ministry of Education, Chongqing Medical University, Chongqing, China., Chen J; Department of Breast and Thyroid Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China., Wang B; Key Laboratory of Laboratory Medical Diagnostics, Chinese Ministry of Education, Chongqing Medical University, Chongqing, China., Tong Y; Key Laboratory of Laboratory Medical Diagnostics, Chinese Ministry of Education, Chongqing Medical University, Chongqing, China., Hai Y; Key Laboratory of Laboratory Medical Diagnostics, Chinese Ministry of Education, Chongqing Medical University, Chongqing, China., Lei M; Department of Breast and Thyroid Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China., Yang X; Key Laboratory of Laboratory Medical Diagnostics, Chinese Ministry of Education, Chongqing Medical University, Chongqing, China., Gan Y; Key Laboratory of Laboratory Medical Diagnostics, Chinese Ministry of Education, Chongqing Medical University, Chongqing, China., Deng C; Key Laboratory of Laboratory Medical Diagnostics, Chinese Ministry of Education, Chongqing Medical University, Chongqing, China., Dai P; Key Laboratory of Laboratory Medical Diagnostics, Chinese Ministry of Education, Chongqing Medical University, Chongqing, China., Liu M; Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. manranliu@cqmu.edu.cn.; Key Laboratory of Laboratory Medical Diagnostics, Chinese Ministry of Education, Chongqing Medical University, Chongqing, China. manranliu@cqmu.edu.cn.; Department of Breast Surgery, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, China. manranliu@cqmu.edu.cn., Tang X; Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. tangxi@hospital.cqmu.edu.cn.
Source: Cell death discovery [Cell Death Discov] 2026 Jan 09; Vol. 12 (1), pp. 11. Date of Electronic Publication: 2026 Jan 09.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2058-7716
DOI:10.1038/s41420-025-02835-9