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Ultrasound stimulation increases cartilage synthesis and revert dedifferentiation on human chondrocytes.

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Title: Ultrasound stimulation increases cartilage synthesis and revert dedifferentiation on human chondrocytes.
Authors: Oliveira S; CMEMS-UMinho, University of Minho, Guimarães, 4800-058, Portugal. sofiaoliveira@dem.uminho.pt., Ferreira D; CEB-Centre of Biological Engineering, University of Minho, Campus de Gualtar, Braga, 4710-057, Portugal.; LABBELS-Associate Laboratory, Braga/Guimarães, 4710-057, Portugal., Padrão J; Centre for Textile Science and Technology (2C2T), Department of Textile Engineering, University of Minho, Campus of Azurém, Guimarães, 4800-058, Portugal., Catarino SO; CMEMS-UMinho, University of Minho, Guimarães, 4800-058, Portugal.; LABBELS-Associate Laboratory, Braga/Guimarães, 4710-057, Portugal., Monteiro F; CMEMS-UMinho, University of Minho, Guimarães, 4800-058, Portugal.; ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães, Portugal., Zille A; Centre for Textile Science and Technology (2C2T), Department of Textile Engineering, University of Minho, Campus of Azurém, Guimarães, 4800-058, Portugal., Rodrigues LR; CEB-Centre of Biological Engineering, University of Minho, Campus de Gualtar, Braga, 4710-057, Portugal.; LABBELS-Associate Laboratory, Braga/Guimarães, 4710-057, Portugal., Silva FS; CMEMS-UMinho, University of Minho, Guimarães, 4800-058, Portugal.; LABBELS-Associate Laboratory, Braga/Guimarães, 4710-057, Portugal., Hinckel BB; Department of Orthopaedic Surgery, William Beaumont Hospital, Royal Oak, MI, USA., Carvalho Ó; CMEMS-UMinho, University of Minho, Guimarães, 4800-058, Portugal.; LABBELS-Associate Laboratory, Braga/Guimarães, 4710-057, Portugal., Leal A; CMEMS-UMinho, University of Minho, Guimarães, 4800-058, Portugal.; LABBELS-Associate Laboratory, Braga/Guimarães, 4710-057, Portugal.; Dom Henrique Research Centre, Porto, Portugal.
Source: Scientific reports [Sci Rep] 2026 Jan 09; Vol. 16 (1), pp. 4498. Date of Electronic Publication: 2026 Jan 09.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: Ultrasound stimulation increases cartilage synthesis and revert dedifferentiation on human chondrocytes.
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  Data: <searchLink fieldCode="AU" term="%22Oliveira+S%22">Oliveira S</searchLink>; CMEMS-UMinho, University of Minho, Guimarães, 4800-058, Portugal. sofiaoliveira@dem.uminho.pt.<br /><searchLink fieldCode="AU" term="%22Ferreira+D%22">Ferreira D</searchLink>; CEB-Centre of Biological Engineering, University of Minho, Campus de Gualtar, Braga, 4710-057, Portugal.; LABBELS-Associate Laboratory, Braga/Guimarães, 4710-057, Portugal.<br /><searchLink fieldCode="AU" term="%22Padrão+J%22">Padrão J</searchLink>; Centre for Textile Science and Technology (2C2T), Department of Textile Engineering, University of Minho, Campus of Azurém, Guimarães, 4800-058, Portugal.<br /><searchLink fieldCode="AU" term="%22Catarino+SO%22">Catarino SO</searchLink>; CMEMS-UMinho, University of Minho, Guimarães, 4800-058, Portugal.; LABBELS-Associate Laboratory, Braga/Guimarães, 4710-057, Portugal.<br /><searchLink fieldCode="AU" term="%22Monteiro+F%22">Monteiro F</searchLink>; CMEMS-UMinho, University of Minho, Guimarães, 4800-058, Portugal.; ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães, Portugal.<br /><searchLink fieldCode="AU" term="%22Zille+A%22">Zille A</searchLink>; Centre for Textile Science and Technology (2C2T), Department of Textile Engineering, University of Minho, Campus of Azurém, Guimarães, 4800-058, Portugal.<br /><searchLink fieldCode="AU" term="%22Rodrigues+LR%22">Rodrigues LR</searchLink>; CEB-Centre of Biological Engineering, University of Minho, Campus de Gualtar, Braga, 4710-057, Portugal.; LABBELS-Associate Laboratory, Braga/Guimarães, 4710-057, Portugal.<br /><searchLink fieldCode="AU" term="%22Silva+FS%22">Silva FS</searchLink>; CMEMS-UMinho, University of Minho, Guimarães, 4800-058, Portugal.; LABBELS-Associate Laboratory, Braga/Guimarães, 4710-057, Portugal.<br /><searchLink fieldCode="AU" term="%22Hinckel+BB%22">Hinckel BB</searchLink>; Department of Orthopaedic Surgery, William Beaumont Hospital, Royal Oak, MI, USA.<br /><searchLink fieldCode="AU" term="%22Carvalho+Ó%22">Carvalho Ó</searchLink>; CMEMS-UMinho, University of Minho, Guimarães, 4800-058, Portugal.; LABBELS-Associate Laboratory, Braga/Guimarães, 4710-057, Portugal.<br /><searchLink fieldCode="AU" term="%22Leal+A%22">Leal A</searchLink>; CMEMS-UMinho, University of Minho, Guimarães, 4800-058, Portugal.; LABBELS-Associate Laboratory, Braga/Guimarães, 4710-057, Portugal.; Dom Henrique Research Centre, Porto, Portugal.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2026 Jan 09; Vol. 16 (1), pp. 4498. <i>Date of Electronic Publication: </i>2026 Jan 09.
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              Text: 2026 Jan 09
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