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Engineered CD40-biosensor-expressing Treg cells as a cell therapy approach for inflammatory diseases.

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Title: Engineered CD40-biosensor-expressing Treg cells as a cell therapy approach for inflammatory diseases.
Authors: Bittner S; Leibniz Institute for Immunotherapy (LIT), University Regensburg, 93053 Regensburg, Germany., Schmidleithner L; Leibniz Institute for Immunotherapy (LIT), University Regensburg, 93053 Regensburg, Germany., Ruhland B; Leibniz Institute for Immunotherapy (LIT), University Regensburg, 93053 Regensburg, Germany., Hofmann V; Leibniz Institute for Immunotherapy (LIT), University Regensburg, 93053 Regensburg, Germany., Stüve P; Leibniz Institute for Immunotherapy (LIT), University Regensburg, 93053 Regensburg, Germany., Hoffmann F; Leibniz Institute for Immunotherapy (LIT), University Regensburg, 93053 Regensburg, Germany., Echtenacher B; Leibniz Institute for Immunotherapy (LIT), University Regensburg, 93053 Regensburg, Germany., Hoffmann P; Leibniz Institute for Immunotherapy (LIT), University Regensburg, 93053 Regensburg, Germany; Department of Internal Medicine III, University Hospital Regensburg, 93053 Regensburg, Germany., Edinger M; Leibniz Institute for Immunotherapy (LIT), University Regensburg, 93053 Regensburg, Germany; Department of Internal Medicine III, University Hospital Regensburg, 93053 Regensburg, Germany., Beilhack A; Department of Internal Medicine II, Interdisciplinary Center for Clinical Research (IZKF) Laboratory Würzburg, Center for Experimental Molecular Medicine, University Hospital Würzburg, 97078 Würzburg, Germany., Strieder N; Leibniz Institute for Immunotherapy (LIT), University Regensburg, 93053 Regensburg, Germany., Hernandez-Lopez I; Leibniz Institute for Immunotherapy (LIT), University Regensburg, 93053 Regensburg, Germany., Rehli M; Leibniz Institute for Immunotherapy (LIT), University Regensburg, 93053 Regensburg, Germany; Department of Internal Medicine III, University Hospital Regensburg, 93053 Regensburg, Germany., Hehlgans T; Leibniz Institute for Immunotherapy (LIT), University Regensburg, 93053 Regensburg, Germany; Chair for Immunology, University Regensburg, 93053 Regensburg, Germany., Feuerer M; Leibniz Institute for Immunotherapy (LIT), University Regensburg, 93053 Regensburg, Germany; Chair for Immunology, University Regensburg, 93053 Regensburg, Germany. Electronic address: markus.feuerer@ukr.de.
Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2026 Apr 01; Vol. 34 (4), pp. 2217-2235. Date of Electronic Publication: 2026 Jan 10.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1525-0024
DOI:10.1016/j.ymthe.2026.01.002