A compartmentalized inflammatory landscape and macrophage plasticity regulate Tet2+/--mediated clonal hematopoiesis.

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Title: A compartmentalized inflammatory landscape and macrophage plasticity regulate Tet2+/--mediated clonal hematopoiesis.
Authors: Lee K; Department of Biomedical Engineering, University of Rochester, Rochester, NY.; Department of Orthopaedics, Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY., Hong CL; Department of Orthopaedics, Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY.; Department of Physiology and Pharmacology, University of Rochester Medical Center, Rochester, NY., Dissanayake W; Department of Orthopaedics, Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY.; Department of Biology, University of Rochester, Rochester, NY., Kulzhanova G; Department of Biomedical Engineering, University of Rochester, Rochester, NY.; Department of Orthopaedics, Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY., Pfeffer AN; Department of Physiology and Pharmacology, University of Rochester Medical Center, Rochester, NY., Li H; Department of Orthopaedics, Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY., Sivakumar S; Department of Biology, University of Rochester, Rochester, NY., Yin Z; Institute of Optics, University of Rochester, Rochester, NY., Quarato ER; Department of Toxicology, University of Rochester Medical Center, Rochester, NY.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY., Benoodt L; Genomics Research Center, University of Rochester Medical Center, Rochester, NY., Bajaj J; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY.; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY., Cao C; Department of Orthopaedics, Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY.; Department of Physiology and Pharmacology, University of Rochester Medical Center, Rochester, NY., Wu CL; Department of Biomedical Engineering, University of Rochester, Rochester, NY.; Department of Orthopaedics, Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY., Calvi LM; Department of Orthopaedics, Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY.; Department of Medicine, University of Rochester Medical Center, Rochester, NY., Yeh SA; Department of Biomedical Engineering, University of Rochester, Rochester, NY.; Department of Orthopaedics, Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY.; Department of Physiology and Pharmacology, University of Rochester Medical Center, Rochester, NY.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY.
Source: Blood [Blood] 2026 Apr 16; Vol. 147 (16), pp. 1828-1841.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1528-0020
DOI:10.1182/blood.2024028031