Hydrogen/deuterium exchange mass spectrometry analysis of ribosome-nascent chain complexes to study protein biogenesis at the peptide level.
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| Title: | Hydrogen/deuterium exchange mass spectrometry analysis of ribosome-nascent chain complexes to study protein biogenesis at the peptide level. |
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| Authors: | Roeselová A; Protein Biogenesis Laboratory, The Francis Crick Institute, London, UK., Pajak A; Protein Biogenesis Laboratory, The Francis Crick Institute, London, UK., Wales TE; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA, USA., Pellowe GA; Protein Biogenesis Laboratory, The Francis Crick Institute, London, UK.; Aston Institute for Membrane Excellence, Aston University, Birmingham, UK., Kjær S; Structural Biology Science Technology Platform, The Francis Crick Institute, London, UK., Engen JR; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA, USA. j.engen@northeastern.edu., Balchin D; Protein Biogenesis Laboratory, The Francis Crick Institute, London, UK. david.balchin@crick.ac.uk. |
| Source: | Nature protocols [Nat Protoc] 2026 May; Vol. 21 (5), pp. 2271-2300. Date of Electronic Publication: 2026 Jan 12. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101284307 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1750-2799 (Electronic) Linking ISSN: 17502799 NLM ISO Abbreviation: Nat Protoc Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1750-2799 |
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| DOI: | 10.1038/s41596-025-01279-w |
