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(R)-bambuterol ameliorates DSS-induced colitis in mice fed a high-fat diet via modulating immune response, intestinal barrier integrity, gut microbiota, and metabolomic profiles.

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Title: (R)-bambuterol ameliorates DSS-induced colitis in mice fed a high-fat diet via modulating immune response, intestinal barrier integrity, gut microbiota, and metabolomic profiles.
Authors: Deng L; Department of Anorectal Surgery, The tenth Affiliated Hospital, Southern Medical University (Dongguan People's Hospital), Dongguan, 523059, China., Tian L; Department of Anorectal Surgery, The tenth Affiliated Hospital, Southern Medical University (Dongguan People's Hospital), Dongguan, 523059, China; Shenzhen School of Clinical Medicine, Southern Medical University, Shenzhen, 518100, China., Su D; Department of Anorectal Surgery, The Sixth Affiliated Hospital of Sun Yatsen University, Guangzhou, 510665, China., Li Y; Department of Anorectal Surgery, The tenth Affiliated Hospital, Southern Medical University (Dongguan People's Hospital), Dongguan, 523059, China., Zhang S; Department of Anorectal Surgery, The tenth Affiliated Hospital, Southern Medical University (Dongguan People's Hospital), Dongguan, 523059, China., Wang S; Institute of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, Guangdong, China., Liu Z; Department of Anorectal Surgery, The tenth Affiliated Hospital, Southern Medical University (Dongguan People's Hospital), Dongguan, 523059, China. Electronic address: liuzhihualzh@hotmail.com.
Source: Archives of biochemistry and biophysics [Arch Biochem Biophys] 2026 Mar; Vol. 777, pp. 110734. Date of Electronic Publication: 2026 Jan 12.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372430 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0384 (Electronic) Linking ISSN: 00039861 NLM ISO Abbreviation: Arch Biochem Biophys Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1096-0384
DOI:10.1016/j.abb.2026.110734