CD47 destabilization via manipulating the SPOP-USP2 axis augments macrophage phagocytosis and cancer immunotherapy.

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Bibliographic Details
Title: CD47 destabilization via manipulating the SPOP-USP2 axis augments macrophage phagocytosis and cancer immunotherapy.
Authors: Yan P; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Bu X; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Hou T; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Chen L; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Zhong G; Institute of Modern Biology, Nanjing University, Nanjing, Jiangsu, China., Huang D; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Wang J; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Qi Y; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Jiang W; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Li Z; Institute of Modern Biology, Nanjing University, Nanjing, Jiangsu, China., Xue X; Department of Neurology & F.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, Massachusetts, USA., Gao Y; Department of Urology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China., Liu J; Department of Urology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China., Inuzuka H; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Freeman GJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA wwei2@bidmc.harvard.edu xdai@nju.edu.cn gordon_freeman@dfci.harvard.edu., Wei W; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA wwei2@bidmc.harvard.edu xdai@nju.edu.cn gordon_freeman@dfci.harvard.edu., Dai X; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA wwei2@bidmc.harvard.edu xdai@nju.edu.cn gordon_freeman@dfci.harvard.edu.; Institute of Modern Biology, Nanjing University, Nanjing, Jiangsu, China.; Division of Hepatobiliary and Transplantation Surgery, Department of General Surgery, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, Jiangsu, China.
Source: Journal for immunotherapy of cancer [J Immunother Cancer] 2026 Jan 14; Vol. 14 (1). Date of Electronic Publication: 2026 Jan 14.
Publication Type: Journal Article
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2051-1426
DOI:10.1136/jitc-2025-013498