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Breathing lung-on-chip: a versatile tool for assessing respiratory toxicity across multiple therapeutic modalities.

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Bibliographic Details
Title: Breathing lung-on-chip: a versatile tool for assessing respiratory toxicity across multiple therapeutic modalities.
Authors: Johansson L; Biopharma Safety, Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.; Department of Immunotechnology, Lund University, Lund, Sweden., Raggi G; AlveoliX AG, Swiss Organs-on-Chip Innovation, Bern, Switzerland., Cartwright J; Pathology, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Cambridge, UK., Lindqvist J; Integrated Bioanalysis, Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Froment L; AlveoliX AG, Swiss Organs-on-Chip Innovation, Bern, Switzerland., Andersson P; Safety Innovation, Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Betts C; Immune Safety, Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Hornberg JJ; Safety Sciences, Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Hobi N; AlveoliX AG, Swiss Organs-on-Chip Innovation, Bern, Switzerland., Ollerstam A; Biopharma Safety, Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Fitzpatrick P; Biopharma Safety, Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden. paul.fitzpatrick2@astrazeneca.com.
Source: Archives of toxicology [Arch Toxicol] 2026 Apr; Vol. 100 (4), pp. 1465-1484. Date of Electronic Publication: 2026 Jan 14.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1432-0738
DOI:10.1007/s00204-025-04269-9