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Single-cell transcriptomics of acetaminophen-induced responses in human 2D and 3D liver microtissues.

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Title: Single-cell transcriptomics of acetaminophen-induced responses in human 2D and 3D liver microtissues.
Authors: Bwanya B; Department of Translational Genomics, GROW Research Institute for Oncology and Developmental Biology, Maastricht University, 6229 ER, Maastricht, The Netherlands., Verheijen MCT; Department of Translational Genomics, GROW Research Institute for Oncology and Developmental Biology, Maastricht University, 6229 ER, Maastricht, The Netherlands., Hauser D; Department of Translational Genomics, GROW Research Institute for Oncology and Developmental Biology, Maastricht University, 6229 ER, Maastricht, The Netherlands., de Kok TM; Department of Translational Genomics, GROW Research Institute for Oncology and Developmental Biology, Maastricht University, 6229 ER, Maastricht, The Netherlands., Jennen DGJ; Department of Translational Genomics, GROW Research Institute for Oncology and Developmental Biology, Maastricht University, 6229 ER, Maastricht, The Netherlands., van den Beucken T; Department of Translational Genomics, GROW Research Institute for Oncology and Developmental Biology, Maastricht University, 6229 ER, Maastricht, The Netherlands., Caiment F; Department of Translational Genomics, GROW Research Institute for Oncology and Developmental Biology, Maastricht University, 6229 ER, Maastricht, The Netherlands. florian.caiment@maastrichtuniversity.nl.
Source: Archives of toxicology [Arch Toxicol] 2026 Apr; Vol. 100 (4), pp. 1411-1424. Date of Electronic Publication: 2026 Jan 14.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1432-0738
DOI:10.1007/s00204-025-04296-6