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The Knowledge Connector decision support system for multiomics-based precision oncology.

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Title: The Knowledge Connector decision support system for multiomics-based precision oncology.
Authors: Hübschmann D; Computational Oncology Group, Molecular Precision Oncology Program, National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between the German Cancer Research Center (DKFZ) and Heidelberg University Hospital, Heidelberg, Germany. d.huebschmann@dkfz-heidelberg.de.; Pattern Recognition and Digital Medicine Group, Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany. d.huebschmann@dkfz-heidelberg.de.; German Cancer Consortium (DKTK), DKFZ, Core Center Heidelberg, Heidelberg, Germany. d.huebschmann@dkfz-heidelberg.de.; Innovation and Service Unit for Bioinformatics and Precision Medicine, DKFZ, Heidelberg, Germany. d.huebschmann@dkfz-heidelberg.de.; Institute of Human Genetics, Heidelberg University Hospital, Heidelberg, Germany. d.huebschmann@dkfz-heidelberg.de., Kreutzfeldt S; German Cancer Consortium (DKTK), DKFZ, Core Center Heidelberg, Heidelberg, Germany.; Division of Translational Medical Oncology, DKFZ, and NCT Heidelberg, Heidelberg, Germany., Roth B; Secondary Use of Data in Oncology Group, Clinical Trial Office, DKFZ, Heidelberg, Germany., Glocker K; Secondary Use of Data in Oncology Group, Clinical Trial Office, DKFZ, Heidelberg, Germany.; Medical Genetics Center, Munich, Germany., Schoop J; Secondary Use of Data in Oncology Group, Clinical Trial Office, DKFZ, Heidelberg, Germany., Oeser L; Secondary Use of Data in Oncology Group, Clinical Trial Office, DKFZ, Heidelberg, Germany., Hausmann S; Secondary Use of Data in Oncology Group, Clinical Trial Office, DKFZ, Heidelberg, Germany., Koch C; Secondary Use of Data in Oncology Group, Clinical Trial Office, DKFZ, Heidelberg, Germany., Uhrig S; Computational Oncology Group, Molecular Precision Oncology Program, National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between the German Cancer Research Center (DKFZ) and Heidelberg University Hospital, Heidelberg, Germany., Hüllein J; Computational Oncology Group, Molecular Precision Oncology Program, National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between the German Cancer Research Center (DKFZ) and Heidelberg University Hospital, Heidelberg, Germany., Hutter B; Computational Oncology Group, Molecular Precision Oncology Program, National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between the German Cancer Research Center (DKFZ) and Heidelberg University Hospital, Heidelberg, Germany., Fröhlich M; Computational Oncology Group, Molecular Precision Oncology Program, National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between the German Cancer Research Center (DKFZ) and Heidelberg University Hospital, Heidelberg, Germany., Heilig CE; Division of Translational Medical Oncology, DKFZ, and NCT Heidelberg, Heidelberg, Germany., Teleanu MV; Division of Translational Medical Oncology, DKFZ, and NCT Heidelberg, Heidelberg, Germany., Lipka DB; German Cancer Consortium (DKTK), DKFZ, Core Center Heidelberg, Heidelberg, Germany.; Division of Translational Medical Oncology, DKFZ, and NCT Heidelberg, Heidelberg, Germany., Kerle IA; Department of Translational Medical Oncology, NCT, NCT/University Cancer Center (NCT/UCC) Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; Translational Medical Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.; DKTK, Partner Site Dresden, Dresden, Germany., Baude-Müller A; Division of Translational Medical Oncology, DKFZ, and NCT Heidelberg, Heidelberg, Germany., Beck K; Division of Translational Medical Oncology, DKFZ, and NCT Heidelberg, Heidelberg, Germany., Heining C; Department of Translational Medical Oncology, NCT, NCT/University Cancer Center (NCT/UCC) Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; Translational Medical Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.; DKTK, Partner Site Dresden, Dresden, Germany., Glimm H; Department of Translational Medical Oncology, NCT, NCT/University Cancer Center (NCT/UCC) Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; Translational Medical Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.; DKTK, Partner Site Dresden, Dresden, Germany., Ückert F; Institute for Applied Medical Informatics, Medical Center Hamburg-Eppendorf, Hamburg, Germany., Knurr A; Secondary Use of Data in Oncology Group, Clinical Trial Office, DKFZ, Heidelberg, Germany., Fröhling S; German Cancer Consortium (DKTK), DKFZ, Core Center Heidelberg, Heidelberg, Germany. stefan.froehling@nct-heidelberg.de.; Institute of Human Genetics, Heidelberg University Hospital, Heidelberg, Germany. stefan.froehling@nct-heidelberg.de.; Division of Translational Medical Oncology, DKFZ, and NCT Heidelberg, Heidelberg, Germany. stefan.froehling@nct-heidelberg.de., Horak P; German Cancer Consortium (DKTK), DKFZ, Core Center Heidelberg, Heidelberg, Germany. peter.horak@nct-heidelberg.de.; Division of Translational Medical Oncology, DKFZ, and NCT Heidelberg, Heidelberg, Germany. peter.horak@nct-heidelberg.de.
Source: Nature communications [Nat Commun] 2026 Jan 19; Vol. 17 (1), pp. 742. Date of Electronic Publication: 2026 Jan 19.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Hübschmann+D%22">Hübschmann D</searchLink>; Computational Oncology Group, Molecular Precision Oncology Program, National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between the German Cancer Research Center (DKFZ) and Heidelberg University Hospital, Heidelberg, Germany. d.huebschmann@dkfz-heidelberg.de.; Pattern Recognition and Digital Medicine Group, Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany. d.huebschmann@dkfz-heidelberg.de.; German Cancer Consortium (DKTK), DKFZ, Core Center Heidelberg, Heidelberg, Germany. d.huebschmann@dkfz-heidelberg.de.; Innovation and Service Unit for Bioinformatics and Precision Medicine, DKFZ, Heidelberg, Germany. d.huebschmann@dkfz-heidelberg.de.; Institute of Human Genetics, Heidelberg University Hospital, Heidelberg, Germany. d.huebschmann@dkfz-heidelberg.de.<br /><searchLink fieldCode="AU" term="%22Kreutzfeldt+S%22">Kreutzfeldt S</searchLink>; 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DKTK, Partner Site Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Glimm+H%22">Glimm H</searchLink>; Department of Translational Medical Oncology, NCT, NCT/University Cancer Center (NCT/UCC) Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; Translational Medical Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.; DKTK, Partner Site Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Ückert+F%22">Ückert F</searchLink>; Institute for Applied Medical Informatics, Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Knurr+A%22">Knurr A</searchLink>; Secondary Use of Data in Oncology Group, Clinical Trial Office, DKFZ, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Fröhling+S%22">Fröhling S</searchLink>; German Cancer Consortium (DKTK), DKFZ, Core Center Heidelberg, Heidelberg, Germany. stefan.froehling@nct-heidelberg.de.; Institute of Human Genetics, Heidelberg University Hospital, Heidelberg, Germany. stefan.froehling@nct-heidelberg.de.; Division of Translational Medical Oncology, DKFZ, and NCT Heidelberg, Heidelberg, Germany. stefan.froehling@nct-heidelberg.de.<br /><searchLink fieldCode="AU" term="%22Horak+P%22">Horak P</searchLink>; German Cancer Consortium (DKTK), DKFZ, Core Center Heidelberg, Heidelberg, Germany. peter.horak@nct-heidelberg.de.; Division of Translational Medical Oncology, DKFZ, and NCT Heidelberg, Heidelberg, Germany. peter.horak@nct-heidelberg.de.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2026 Jan 19; Vol. 17 (1), pp. 742. <i>Date of Electronic Publication: </i>2026 Jan 19.
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