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Challenging Additivity: Comparing Predicted and Observed AhR Activity of Polycyclic Aromatic Compound (PAC) Mixtures Containing Active and Inactive Constituents.

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Bibliographic Details
Title: Challenging Additivity: Comparing Predicted and Observed AhR Activity of Polycyclic Aromatic Compound (PAC) Mixtures Containing Active and Inactive Constituents.
Authors: Eccles KM; Environmental Health Science and Research Bureau, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario K1A 0K9, Canada., Gaston K; Oak Ridge Institute for Science Education, Oak Ridge, Tennessee 37830, United States., Green EM; Oak Ridge Institute for Science Education, Oak Ridge, Tennessee 37830, United States., Waidyanatha S; Division of Translational Toxicology, National Institute of Environmental Health Sciences, Durham, North Carolina 27709, United States., Stiffler B; Battelle, Columbus, Ohio 43201, United States., Harris SF; DLH, LLC, Bethesda, Maryland 20814, United States., Rider CV; Division of Translational Toxicology, National Institute of Environmental Health Sciences, Durham, North Carolina 27709, United States., Medlock Kakaley E; Center for Public Health and Environmental Assessment, Public Health and Integrated Toxicology Division, U.S Environmental Protection Agency, Durham, North Carolina 27709, United States.
Source: Environmental science & technology [Environ Sci Technol] 2026 Feb 03; Vol. 60 (4), pp. 2976-2987. Date of Electronic Publication: 2026 Jan 21.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0213155 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5851 (Electronic) Linking ISSN: 0013936X NLM ISO Abbreviation: Environ Sci Technol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1520-5851
DOI:10.1021/acs.est.5c11914