Challenging Additivity: Comparing Predicted and Observed AhR Activity of Polycyclic Aromatic Compound (PAC) Mixtures Containing Active and Inactive Constituents.
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| Title: | Challenging Additivity: Comparing Predicted and Observed AhR Activity of Polycyclic Aromatic Compound (PAC) Mixtures Containing Active and Inactive Constituents. |
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| Authors: | Eccles KM; Environmental Health Science and Research Bureau, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario K1A 0K9, Canada., Gaston K; Oak Ridge Institute for Science Education, Oak Ridge, Tennessee 37830, United States., Green EM; Oak Ridge Institute for Science Education, Oak Ridge, Tennessee 37830, United States., Waidyanatha S; Division of Translational Toxicology, National Institute of Environmental Health Sciences, Durham, North Carolina 27709, United States., Stiffler B; Battelle, Columbus, Ohio 43201, United States., Harris SF; DLH, LLC, Bethesda, Maryland 20814, United States., Rider CV; Division of Translational Toxicology, National Institute of Environmental Health Sciences, Durham, North Carolina 27709, United States., Medlock Kakaley E; Center for Public Health and Environmental Assessment, Public Health and Integrated Toxicology Division, U.S Environmental Protection Agency, Durham, North Carolina 27709, United States. |
| Source: | Environmental science & technology [Environ Sci Technol] 2026 Feb 03; Vol. 60 (4), pp. 2976-2987. Date of Electronic Publication: 2026 Jan 21. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 0213155 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5851 (Electronic) Linking ISSN: 0013936X NLM ISO Abbreviation: Environ Sci Technol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41563147 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Challenging Additivity: Comparing Predicted and Observed AhR Activity of Polycyclic Aromatic Compound (PAC) Mixtures Containing Active and Inactive Constituents. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Eccles+KM%22">Eccles KM</searchLink>; Environmental Health Science and Research Bureau, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario K1A 0K9, Canada.<br /><searchLink fieldCode="AU" term="%22Gaston+K%22">Gaston K</searchLink>; Oak Ridge Institute for Science Education, Oak Ridge, Tennessee 37830, United States.<br /><searchLink fieldCode="AU" term="%22Green+EM%22">Green EM</searchLink>; Oak Ridge Institute for Science Education, Oak Ridge, Tennessee 37830, United States.<br /><searchLink fieldCode="AU" term="%22Waidyanatha+S%22">Waidyanatha S</searchLink>; Division of Translational Toxicology, National Institute of Environmental Health Sciences, Durham, North Carolina 27709, United States.<br /><searchLink fieldCode="AU" term="%22Stiffler+B%22">Stiffler B</searchLink>; Battelle, Columbus, Ohio 43201, United States.<br /><searchLink fieldCode="AU" term="%22Harris+SF%22">Harris SF</searchLink>; DLH, LLC, Bethesda, Maryland 20814, United States.<br /><searchLink fieldCode="AU" term="%22Rider+CV%22">Rider CV</searchLink>; Division of Translational Toxicology, National Institute of Environmental Health Sciences, Durham, North Carolina 27709, United States.<br /><searchLink fieldCode="AU" term="%22Medlock+Kakaley+E%22">Medlock Kakaley E</searchLink>; Center for Public Health and Environmental Assessment, Public Health and Integrated Toxicology Division, U.S Environmental Protection Agency, Durham, North Carolina 27709, United States. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220213155%22">Environmental science & technology</searchLink> [Environ Sci Technol] 2026 Feb 03; Vol. 60 (4), pp. 2976-2987. <i>Date of Electronic Publication: </i>2026 Jan 21. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0213155 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-5851 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220013936X%22">0013936X </searchLink><i>NLM ISO Abbreviation: </i>Environ Sci Technol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41563147 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1021/acs.est.5c11914 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 2976 Titles: – TitleFull: Challenging Additivity: Comparing Predicted and Observed AhR Activity of Polycyclic Aromatic Compound (PAC) Mixtures Containing Active and Inactive Constituents. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Eccles KM – PersonEntity: Name: NameFull: Gaston K – PersonEntity: Name: NameFull: Green EM – PersonEntity: Name: NameFull: Waidyanatha S – PersonEntity: Name: NameFull: Stiffler B – PersonEntity: Name: NameFull: Harris SF – PersonEntity: Name: NameFull: Rider CV – PersonEntity: Name: NameFull: Medlock Kakaley E IsPartOfRelationships: – BibEntity: Dates: – D: 03 M: 02 Text: 2026 Feb 03 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1520-5851 Numbering: – Type: volume Value: 60 – Type: issue Value: 4 Titles: – TitleFull: Environmental science & technology Type: main |
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