CRISPR screens identify PRMT7 as a therapeutic target to enhance T cell-mediated killing in breast cancer.
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| Title: | CRISPR screens identify PRMT7 as a therapeutic target to enhance T cell-mediated killing in breast cancer. |
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| Authors: | Shi W; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia., Luo Y; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia.; Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia., Wang Y; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia., Burrows JM; Infection and Immunology Program, QIMR Berghofer, Brisbane, QLD, Australia., Black D; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia., Civitarese A; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia., Perlaza-Jimenez L; Cancer Research Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., Zhang P; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia., Manning M; Cancer Research Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.; Monash Functional Genomics Platform, Monash University, Clayton, VIC, Australia., Tuano N; Cancer Research Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., Rentería ME; Mental Health and Neuroscience Program, QIMR Berghofer, Brisbane, QLD, Australia., Xiao C; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia., Tey SK; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia., Rosenbluh J; Cancer Research Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.; Monash Functional Genomics Platform, Monash University, Clayton, VIC, Australia., Smith C; Infection and Immunology Program, QIMR Berghofer, Brisbane, QLD, Australia., Chenevix-Trench G; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia., Beesley J; Cancer Research Program, QIMR Berghofer, Brisbane, QLD, Australia. Jonathan.Beesley@qimrb.edu.au.; Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia. Jonathan.Beesley@qimrb.edu.au. |
| Source: | NPJ breast cancer [NPJ Breast Cancer] 2026 Jan 21; Vol. 12 (1), pp. 24. Date of Electronic Publication: 2026 Jan 21. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Breast Cancer Research Foundation Country of Publication: United States NLM ID: 101674891 Publication Model: Electronic Cited Medium: Print ISSN: 2374-4677 (Print) Linking ISSN: 23744677 NLM ISO Abbreviation: NPJ Breast Cancer Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2374-4677 |
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| DOI: | 10.1038/s41523-025-00888-8 |
