View in EDS

Dyslipidemia-associated natural IgM improves oncolytic virus TILT-123 efficacy through antibody-dependent enhancement in solid tumors.

Saved in:
Bibliographic Details
Title: Dyslipidemia-associated natural IgM improves oncolytic virus TILT-123 efficacy through antibody-dependent enhancement in solid tumors.
Authors: Clubb JHA; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland; TILT Biotherapeutics, 00290 Helsinki, Finland., Pakola SA; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland., Joenväärä S; Transplantation Laboratory, Faculty of Medicine, University of Helsinki, Helsinki, Finland; HUSLAB, Helsinki University Hospital, 00290 Helsinki, Finland., Kudling TV; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland; TILT Biotherapeutics, 00290 Helsinki, Finland., Tohmola T; Transplantation Laboratory, Faculty of Medicine, University of Helsinki, Helsinki, Finland; HUSLAB, Helsinki University Hospital, 00290 Helsinki, Finland., Arias V; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland., Jirovec E; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland., van der Heijden M; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland., Quixabeira DCA; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland; TILT Biotherapeutics, 00290 Helsinki, Finland., Pasanen A; Department of Pathology, University of Helsinki and Helsinki University Hospital, 00290 Helsinki, Finland., Haybout L; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland; TILT Biotherapeutics, 00290 Helsinki, Finland., Ojala N; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland., Basnet S; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland., Eleuteri A; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland., Ferrero JD; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland., Hirvenoja S; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland., Svane IM; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital, 2730 Herlev, Denmark., Mäenpää J; Docrates Cancer Center, 00180 Helsinki, Finland., Jalkanen K; Comprehensive Cancer Center, Helsinki University Hospital, 00290 Helsinki, Finland., Block MS; Mayo Clinic Cancer Center, Rochester, MN 55905, USA., Alanko T; Docrates Cancer Center, 00180 Helsinki, Finland., Monberg T; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital, 2730 Herlev, Denmark., Zahraoui S; TILT Biotherapeutics, 00290 Helsinki, Finland., Grönberg-Vähä-Koskela S; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland; Comprehensive Cancer Center, Helsinki University Hospital, 00290 Helsinki, Finland., Salmelin N; IRCM, Insitute de Reserche en Cancérologie de Monpellier, INSERM U1194, University Montpellier, Institute Régional du Cancer Montpellier, Montpellier, France., Kistler C; TILT Biotherapeutics, 00290 Helsinki, Finland., Havunen R; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland; TILT Biotherapeutics, 00290 Helsinki, Finland., Sorsa S; TILT Biotherapeutics, 00290 Helsinki, Finland., Manuel Dos Santos J; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland; TILT Biotherapeutics, 00290 Helsinki, Finland., Cervera-Carrascon V; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland; TILT Biotherapeutics, 00290 Helsinki, Finland., Kanerva A; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland; Department of Obstetrics and Gynecology, Helsinki University Hospital and University of Helsinki, 00290 Helsinki, Finland., Hemminki O; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland; Department of Urology, Helsinki University Hospital, 00290 Helsinki, Finland., Renkonen R; Transplantation Laboratory, Faculty of Medicine, University of Helsinki, Helsinki, Finland; HUSLAB, Helsinki University Hospital, 00290 Helsinki, Finland., Hemminki A; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland; TILT Biotherapeutics, 00290 Helsinki, Finland; Comprehensive Cancer Center, Helsinki University Hospital, 00290 Helsinki, Finland. Electronic address: akseli.hemminki@helsinki.fi.
Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2026 May 06; Vol. 34 (5), pp. 3056-3076. Date of Electronic Publication: 2026 Jan 20.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41566775
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Dyslipidemia-associated natural IgM improves oncolytic virus TILT-123 efficacy through antibody-dependent enhancement in solid tumors.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Clubb+JHA%22">Clubb JHA</searchLink>; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland; TILT Biotherapeutics, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Pakola+SA%22">Pakola SA</searchLink>; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Joenväärä+S%22">Joenväärä S</searchLink>; Transplantation Laboratory, Faculty of Medicine, University of Helsinki, Helsinki, Finland; HUSLAB, Helsinki University Hospital, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Kudling+TV%22">Kudling TV</searchLink>; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland; TILT Biotherapeutics, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Tohmola+T%22">Tohmola T</searchLink>; Transplantation Laboratory, Faculty of Medicine, University of Helsinki, Helsinki, Finland; HUSLAB, Helsinki University Hospital, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Arias+V%22">Arias V</searchLink>; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Jirovec+E%22">Jirovec E</searchLink>; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22van+der+Heijden+M%22">van der Heijden M</searchLink>; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Quixabeira+DCA%22">Quixabeira DCA</searchLink>; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland; TILT Biotherapeutics, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Pasanen+A%22">Pasanen A</searchLink>; Department of Pathology, University of Helsinki and Helsinki University Hospital, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Haybout+L%22">Haybout L</searchLink>; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland; TILT Biotherapeutics, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Ojala+N%22">Ojala N</searchLink>; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Basnet+S%22">Basnet S</searchLink>; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Eleuteri+A%22">Eleuteri A</searchLink>; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Ferrero+JD%22">Ferrero JD</searchLink>; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Hirvenoja+S%22">Hirvenoja S</searchLink>; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Svane+IM%22">Svane IM</searchLink>; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital, 2730 Herlev, Denmark.<br /><searchLink fieldCode="AU" term="%22Mäenpää+J%22">Mäenpää J</searchLink>; Docrates Cancer Center, 00180 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Jalkanen+K%22">Jalkanen K</searchLink>; Comprehensive Cancer Center, Helsinki University Hospital, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Block+MS%22">Block MS</searchLink>; Mayo Clinic Cancer Center, Rochester, MN 55905, USA.<br /><searchLink fieldCode="AU" term="%22Alanko+T%22">Alanko T</searchLink>; Docrates Cancer Center, 00180 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Monberg+T%22">Monberg T</searchLink>; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital, 2730 Herlev, Denmark.<br /><searchLink fieldCode="AU" term="%22Zahraoui+S%22">Zahraoui S</searchLink>; TILT Biotherapeutics, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Grönberg-Vähä-Koskela+S%22">Grönberg-Vähä-Koskela S</searchLink>; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland; Comprehensive Cancer Center, Helsinki University Hospital, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Salmelin+N%22">Salmelin N</searchLink>; IRCM, Insitute de Reserche en Cancérologie de Monpellier, INSERM U1194, University Montpellier, Institute Régional du Cancer Montpellier, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Kistler+C%22">Kistler C</searchLink>; TILT Biotherapeutics, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Havunen+R%22">Havunen R</searchLink>; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland; TILT Biotherapeutics, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Sorsa+S%22">Sorsa S</searchLink>; TILT Biotherapeutics, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Manuel+Dos+Santos+J%22">Manuel Dos Santos J</searchLink>; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland; TILT Biotherapeutics, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Cervera-Carrascon+V%22">Cervera-Carrascon V</searchLink>; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland; TILT Biotherapeutics, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Kanerva+A%22">Kanerva A</searchLink>; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland; Department of Obstetrics and Gynecology, Helsinki University Hospital and University of Helsinki, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Hemminki+O%22">Hemminki O</searchLink>; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland; Department of Urology, Helsinki University Hospital, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Renkonen+R%22">Renkonen R</searchLink>; Transplantation Laboratory, Faculty of Medicine, University of Helsinki, Helsinki, Finland; HUSLAB, Helsinki University Hospital, 00290 Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Hemminki+A%22">Hemminki A</searchLink>; Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland; TILT Biotherapeutics, 00290 Helsinki, Finland; Comprehensive Cancer Center, Helsinki University Hospital, 00290 Helsinki, Finland. Electronic address: akseli.hemminki@helsinki.fi.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22100890581%22">Molecular therapy : the journal of the American Society of Gene Therapy</searchLink> [Mol Ther] 2026 May 06; Vol. 34 (5), pp. 3056-3076. <i>Date of Electronic Publication: </i>2026 Jan 20.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>100890581 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1525-0024 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215250016%22">15250016 </searchLink><i>NLM ISO Abbreviation: </i>Mol Ther <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41566775
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.ymthe.2026.01.019
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 3056
    Titles:
      – TitleFull: Dyslipidemia-associated natural IgM improves oncolytic virus TILT-123 efficacy through antibody-dependent enhancement in solid tumors.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Clubb JHA
      – PersonEntity:
          Name:
            NameFull: Pakola SA
      – PersonEntity:
          Name:
            NameFull: Joenväärä S
      – PersonEntity:
          Name:
            NameFull: Kudling TV
      – PersonEntity:
          Name:
            NameFull: Tohmola T
      – PersonEntity:
          Name:
            NameFull: Arias V
      – PersonEntity:
          Name:
            NameFull: Jirovec E
      – PersonEntity:
          Name:
            NameFull: van der Heijden M
      – PersonEntity:
          Name:
            NameFull: Quixabeira DCA
      – PersonEntity:
          Name:
            NameFull: Pasanen A
      – PersonEntity:
          Name:
            NameFull: Haybout L
      – PersonEntity:
          Name:
            NameFull: Ojala N
      – PersonEntity:
          Name:
            NameFull: Basnet S
      – PersonEntity:
          Name:
            NameFull: Eleuteri A
      – PersonEntity:
          Name:
            NameFull: Ferrero JD
      – PersonEntity:
          Name:
            NameFull: Hirvenoja S
      – PersonEntity:
          Name:
            NameFull: Svane IM
      – PersonEntity:
          Name:
            NameFull: Mäenpää J
      – PersonEntity:
          Name:
            NameFull: Jalkanen K
      – PersonEntity:
          Name:
            NameFull: Block MS
      – PersonEntity:
          Name:
            NameFull: Alanko T
      – PersonEntity:
          Name:
            NameFull: Monberg T
      – PersonEntity:
          Name:
            NameFull: Zahraoui S
      – PersonEntity:
          Name:
            NameFull: Grönberg-Vähä-Koskela S
      – PersonEntity:
          Name:
            NameFull: Salmelin N
      – PersonEntity:
          Name:
            NameFull: Kistler C
      – PersonEntity:
          Name:
            NameFull: Havunen R
      – PersonEntity:
          Name:
            NameFull: Sorsa S
      – PersonEntity:
          Name:
            NameFull: Manuel Dos Santos J
      – PersonEntity:
          Name:
            NameFull: Cervera-Carrascon V
      – PersonEntity:
          Name:
            NameFull: Kanerva A
      – PersonEntity:
          Name:
            NameFull: Hemminki O
      – PersonEntity:
          Name:
            NameFull: Renkonen R
      – PersonEntity:
          Name:
            NameFull: Hemminki A
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 06
              M: 05
              Text: 2026 May 06
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1525-0024
          Numbering:
            – Type: volume
              Value: 34
            – Type: issue
              Value: 5
          Titles:
            – TitleFull: Molecular therapy : the journal of the American Society of Gene Therapy
              Type: main
ResultId 1