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The role of negative pressure wound therapy on TGF-β1, MMP-9, α-SMA, and collagen type III in preventing burn contractures in a porcine model.

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Title: The role of negative pressure wound therapy on TGF-β1, MMP-9, α-SMA, and collagen type III in preventing burn contractures in a porcine model.
Authors: Seswandhana MR; Plastic, Reconstructive, and Aesthetic Surgery Division, Department of Surgery, Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta 55281, Indonesia. Electronic address: rosadi_seswandhana@ugm.ac.id., Gunadi; Pediatric Surgery Division, Department of Surgery/Genetics Working Group/Translational Research Unit, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta 55281, Indonesia. Electronic address: drgunadi@ugm.ac.id., Anwar SL; Division of Surgical Oncology - Department of Surgery, Dr. Sardjito Hospital/Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia., Aryandono T; Division of Surgical Oncology - Department of Surgery, Dr. Sardjito Hospital/Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia., Dachlan I; Plastic, Reconstructive, and Aesthetic Surgery Division, Department of Surgery, Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta 55281, Indonesia., Mulyono B; Clinical Pathology Department, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Jl. Farmako, Senolowo, Sekip Utara, Sleman, Yogyakarta 55281, Indonesia., Widodo I; Department of Pathology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta 55281, Indonesia. Electronic address: irianiwati@ugm.ac.id., Wirohadidjojo YW; Department of Dermatology and Venereology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Dr. Sardjito General Hospital, Yogyakarta 55281, Indonesia. Electronic address: yohanes.widodo@ugm.ac.id., Sukma MPL; Department of Surgery, Dr. Sardjito Hospital/Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia., Adhityo P; Department of Surgery, Dr. Sardjito Hospital/Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia.
Source: Journal of plastic, reconstructive & aesthetic surgery : JPRAS [J Plast Reconstr Aesthet Surg] 2026 Mar; Vol. 114, pp. 58-70. Date of Electronic Publication: 2026 Jan 06.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101264239 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0539 (Electronic) Linking ISSN: 17486815 NLM ISO Abbreviation: J Plast Reconstr Aesthet Surg Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Seswandhana+MR%22">Seswandhana MR</searchLink>; Plastic, Reconstructive, and Aesthetic Surgery Division, Department of Surgery, Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta 55281, Indonesia. Electronic address: rosadi_seswandhana@ugm.ac.id.<br /><searchLink fieldCode="AU" term="%22Gunadi%22">Gunadi</searchLink>; Pediatric Surgery Division, Department of Surgery/Genetics Working Group/Translational Research Unit, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta 55281, Indonesia. Electronic address: drgunadi@ugm.ac.id.<br /><searchLink fieldCode="AU" term="%22Anwar+SL%22">Anwar SL</searchLink>; Division of Surgical Oncology - Department of Surgery, Dr. Sardjito Hospital/Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia.<br /><searchLink fieldCode="AU" term="%22Aryandono+T%22">Aryandono T</searchLink>; Division of Surgical Oncology - Department of Surgery, Dr. Sardjito Hospital/Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia.<br /><searchLink fieldCode="AU" term="%22Dachlan+I%22">Dachlan I</searchLink>; Plastic, Reconstructive, and Aesthetic Surgery Division, Department of Surgery, Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta 55281, Indonesia.<br /><searchLink fieldCode="AU" term="%22Mulyono+B%22">Mulyono B</searchLink>; Clinical Pathology Department, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Jl. Farmako, Senolowo, Sekip Utara, Sleman, Yogyakarta 55281, Indonesia.<br /><searchLink fieldCode="AU" term="%22Widodo+I%22">Widodo I</searchLink>; Department of Pathology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta 55281, Indonesia. Electronic address: irianiwati@ugm.ac.id.<br /><searchLink fieldCode="AU" term="%22Wirohadidjojo+YW%22">Wirohadidjojo YW</searchLink>; Department of Dermatology and Venereology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Dr. Sardjito General Hospital, Yogyakarta 55281, Indonesia. Electronic address: yohanes.widodo@ugm.ac.id.<br /><searchLink fieldCode="AU" term="%22Sukma+MPL%22">Sukma MPL</searchLink>; Department of Surgery, Dr. Sardjito Hospital/Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia.<br /><searchLink fieldCode="AU" term="%22Adhityo+P%22">Adhityo P</searchLink>; Department of Surgery, Dr. Sardjito Hospital/Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101264239 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1878-0539 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217486815%22">17486815 </searchLink><i>NLM ISO Abbreviation: </i>J Plast Reconstr Aesthet Surg <i>Subsets: </i>MEDLINE
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        Text: English
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      – TitleFull: The role of negative pressure wound therapy on TGF-β1, MMP-9, α-SMA, and collagen type III in preventing burn contractures in a porcine model.
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              Text: 2026 Mar
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