Cross-ancestry comparison of aptamer and antibody protein measures.

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Title: Cross-ancestry comparison of aptamer and antibody protein measures.
Authors: Nicholas JC; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Katz DH; Division of Cardiovascular Medicine, Division of Computational Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Tahir UA; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Debban CL; Department of Genome Sciences, University of Virginia, Charlottesville, VA, USA., Aguet F; Broad Institute, Cambridge, MA, USA., Blackwell T; University of Michigan, Ann Arbor, MI, USA., Bowler RP; Genomic Sciences and Systems Biology, Cleveland Clinic Research, Cleveland, OH, USA., Broadaway KA; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Chen J; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Clish CB; Metabolomics Platform, Broad Institute, Cambridge, MA, USA., Coresh J; Department of Population Health, Institute for Optimal Aging, New York, NY, USA., Cornell E; Department of Pathology and Laboratory Medicine, Larner College of Medicine at the University of Vermont, Burlington, VT, USA., Cruz DE; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Deo R; Division of Cardiovascular Medicine, University of Pennsylvania, Philadelphia, PA, USA., Doyle MF; Department of Pathology and Laboratory Medicine, Larner College of Medicine at the University of Vermont, Burlington, VT, USA., Durda P; Department of Pathology and Laboratory Medicine, Larner College of Medicine at the University of Vermont, Burlington, VT, USA., Ekunwe L; University of Mississippi Medical Center, Jackson, MS, USA., Floyd JS; School of Medicine, University of Washington, Seattle, WA, USA., Gill D; Sequoia Genetics, London, UK., Guo X; Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Hoogeveen RC; Division of Cardiovascular Research, Department of Medicine, Baylor College of Medicine, Houston, TX, USA., Johnson C; University of Washington, Seattle, WA, USA., Lange LA; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Li Y; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Manning A; Broad Institute, Boston, MA, USA.; Harvard University, Boston, MA, USA.; Massachusetts General Hospital, Boston, MA, USA., Meigs JB; Department of Medicine, Broad Institute, Boston, MA, USA.; Division of General Internal Medicine, Department of Medicine, Harvard Medical School, Boston, MA, USA., Mi MY; Division of Cardiovascular Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Mychaleckyj JC; Department of Genome Sciences, University of Virginia, Charlottesville, VA, USA., Olson NC; Department of Pathology and Laboratory Medicine, Larner College of Medicine at the University of Vermont, Burlington, VT, USA., Pratte KA; Department of Biostatistics, National Jewish Health, Denver, CO, USA., Psaty BM; Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.; Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA., Reiner AP; Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA, USA., Ruan P; Department of Health Data Science and Biostatistics, University of Texas Southwestern Medical Center, Dallas, TX, USA., Sevilla-Gonzalez M; Clinical and Translational Epidemiology Unit, Mongan Institute, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, MA, USA., Shah AM; Department of Medicine, Division of Cardiology, University of Texas Southwestern Medical Center, Dallas, TX, USA., Sun Q; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.; Center for Computational and Genomic Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Tracy RP; Department of Pathology and Laboratory Medicine, Larner College of Medicine at the University of Vermont, Burlington, VT, USA., Wen J; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Wood AC; Department of Pediatrics, USDA/ARS Children's Nutrition Research Center, Baylor College of Medicine, Houston, TX, USA., Wilson JG; Department of Cardiology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Young KL; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Yu B; Department of Epidemiology and Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Rooney MR; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.; Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Manichaikul A; Department of Genome Sciences, University of Virginia, Charlottesville, VA, USA., Dubin R; UT Southwestern, Dallas, TX, USA., Mohlke KL; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Rich SS; Department of Genome Sciences, University of Virginia, Charlottesville, VA, USA., Rotter JI; Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Ganz P; Division of Cardiology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Gerszten RE; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Taylor KD; Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Raffield LM; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. laura_raffield@unc.edu.
Source: Nature communications [Nat Commun] 2026 Jan 22; Vol. 17 (1), pp. 1054. Date of Electronic Publication: 2026 Jan 22.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/s41467-025-67814-1