Synaptic and intrinsic membrane defects disrupt early neural network dynamics in Down syndrome.

Saved in:
Bibliographic Details
Title: Synaptic and intrinsic membrane defects disrupt early neural network dynamics in Down syndrome.
Authors: Hannan SB; Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK. saadhannan@fas.harvard.edu.; Department of Molecular and Cellular Biology, Harvard University; 52 Oxford Street Cambridge, Cambridge, MA, USA. saadhannan@fas.harvard.edu., Alić I; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Department of Anatomy, Histology and Embryology, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia., Murray A; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Kwon J; Department of Life Science, Chung-Ang University; 84 Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea., Mortensen M; Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK., Kang HJ; Department of Life Science, Chung-Ang University; 84 Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea., Plećaš A; Department of Anatomy, Histology and Embryology, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia., Goh PA; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., O'Brien NL; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Naud R; Department of Cellular and Molecular Medicine, University of Ottawa; 451 Smyth Rd, Ottawa, ON, Canada., Nižetić D; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. d.nizetic@qmul.ac.uk., Smart TG; Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK. t.smart@ucl.ac.uk.
Source: Nature communications [Nat Commun] 2026 Jan 22; Vol. 17 (1), pp. 1287. Date of Electronic Publication: 2026 Jan 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/s41467-025-68048-x