Challenges of monocyte HLA-DR targeted immunomodulation in sepsis-a prospective observational cohort study.

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Title: Challenges of monocyte HLA-DR targeted immunomodulation in sepsis-a prospective observational cohort study.
Authors: Snow TAC; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, United Kingdom., Villa A; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, United Kingdom., Cesar A; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, United Kingdom., Ryckaert F; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, United Kingdom., Saleem N; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, United Kingdom., Smyth D; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, United Kingdom., Pan H; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, United Kingdom., Flint J; Department of Ageing, Rheumatology and Regenerative Medicine, Division of Medicine, University College London, London, United Kingdom., Brealey D; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, United Kingdom.; UCLH NIHR Biomedical Research Centre, University College London Hospitals NHS Foundation Trust, London, United Kingdom., Singer M; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, United Kingdom., Gilroy DW; Department of Ageing, Rheumatology and Regenerative Medicine, Division of Medicine, University College London, London, United Kingdom., Arulkumaran N; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, United Kingdom.
Corporate Authors: University College London Hospitals Critical Care Research Team
Source: Frontiers in immunology [Front Immunol] 2026 Jan 07; Vol. 16, pp. 1709289. Date of Electronic Publication: 2026 Jan 07 (Print Publication: 2025).
Publication Type: Journal Article; Observational Study
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2025.1709289