Insights into the human pharmacokinetics and metabolism of branaplam, a splicing modulator of a survival motor neuron-2 and huntingtin pre-mRNAs, in infants and adults.
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| Title: | Insights into the human pharmacokinetics and metabolism of branaplam, a splicing modulator of a survival motor neuron-2 and huntingtin pre-mRNAs, in infants and adults. |
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| Authors: | Lozac'h F; Pharmacokinetic Sciences, Biomedical Research, Novartis Pharma AG, Basel, Switzerland. Electronic address: frederic.lozach@novartis.com., Demailly A; Pharmacokinetic Sciences, Biomedical Research, Novartis Pharma AG, Basel, Switzerland., Raccuglia M; Pharmacokinetic Sciences, Biomedical Research, Novartis Pharma AG, Basel, Switzerland., James AD; Pharmacokinetic Sciences, Biomedical Research, Novartis Pharma AG, Basel, Switzerland., Walles M; Pharmacokinetic Sciences, Biomedical Research, Novartis Pharma AG, Basel, Switzerland., Borowsky B; Global Medical Affairs, Global Drug Development, Novartis Pharma AG, Basel, Switzerland., Faller T; Pharmacokinetic Sciences, Biomedical Research, Novartis Pharma AG, Basel, Switzerland. |
| Source: | Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2026 Feb; Vol. 54 (2), pp. 100219. Date of Electronic Publication: 2025 Dec 13. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Society for Pharmacology and Experimental Therapeutics, etc.] Country of Publication: Netherlands NLM ID: 9421550 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-009X (Electronic) Linking ISSN: 00909556 NLM ISO Abbreviation: Drug Metab Dispos Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1521-009X |
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| DOI: | 10.1016/j.dmd.2025.100219 |
