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Dual-TERM enables simultaneous profiling of 5' and 3' terminal modifications in small RNAs by integrating enzymatic treatment with PBA-PAGE.

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Title: Dual-TERM enables simultaneous profiling of 5' and 3' terminal modifications in small RNAs by integrating enzymatic treatment with PBA-PAGE.
Authors: Yang H; State Key Laboratory of Genetics and Development of Complex Phenotypes, Zhangjiang mRNA Innovation and Translation Center, School of Life Sciences, Fudan University, Shanghai, 200438, PR China., Zhang B; State Key Laboratory of Genetics and Development of Complex Phenotypes, Zhangjiang mRNA Innovation and Translation Center, School of Life Sciences, Fudan University, Shanghai, 200438, PR China., Zhu S; State Key Laboratory of Genetics and Development of Complex Phenotypes, Zhangjiang mRNA Innovation and Translation Center, School of Life Sciences, Fudan University, Shanghai, 200438, PR China., Zhang S; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, PR China., Yu X; State Key Laboratory of Genetics and Development of Complex Phenotypes, Zhangjiang mRNA Innovation and Translation Center, School of Life Sciences, Fudan University, Shanghai, 200438, PR China., Zhang L; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, PR China; Department of Pharmaceutical Botany, School of Pharmacy, Naval Medical University, Shanghai, 200438, PR China. Electronic address: zhanglei@smmu.edu.cn., Ren G; State Key Laboratory of Genetics and Development of Complex Phenotypes, Zhangjiang mRNA Innovation and Translation Center, School of Life Sciences, Fudan University, Shanghai, 200438, PR China. Electronic address: gdren@fudan.edu.cn., Chen S; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, PR China; Department of Pharmaceutical Botany, School of Pharmacy, Naval Medical University, Shanghai, 200438, PR China; State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Beijing, 100700, PR China. Electronic address: sschen@shutcm.edu.cn.
Source: International journal of biological macromolecules [Int J Biol Macromol] 2026 Feb; Vol. 344 (Pt 1), pp. 150467. Date of Electronic Publication: 2026 Jan 23.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Dual-TERM enables simultaneous profiling of 5' and 3' terminal modifications in small RNAs by integrating enzymatic treatment with PBA-PAGE.
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  Data: <searchLink fieldCode="AU" term="%22Yang+H%22">Yang H</searchLink>; State Key Laboratory of Genetics and Development of Complex Phenotypes, Zhangjiang mRNA Innovation and Translation Center, School of Life Sciences, Fudan University, Shanghai, 200438, PR China.<br /><searchLink fieldCode="AU" term="%22Zhang+B%22">Zhang B</searchLink>; State Key Laboratory of Genetics and Development of Complex Phenotypes, Zhangjiang mRNA Innovation and Translation Center, School of Life Sciences, Fudan University, Shanghai, 200438, PR China.<br /><searchLink fieldCode="AU" term="%22Zhu+S%22">Zhu S</searchLink>; State Key Laboratory of Genetics and Development of Complex Phenotypes, Zhangjiang mRNA Innovation and Translation Center, School of Life Sciences, Fudan University, Shanghai, 200438, PR China.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, PR China.<br /><searchLink fieldCode="AU" term="%22Yu+X%22">Yu X</searchLink>; State Key Laboratory of Genetics and Development of Complex Phenotypes, Zhangjiang mRNA Innovation and Translation Center, School of Life Sciences, Fudan University, Shanghai, 200438, PR China.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, PR China; Department of Pharmaceutical Botany, School of Pharmacy, Naval Medical University, Shanghai, 200438, PR China. Electronic address: zhanglei@smmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Ren+G%22">Ren G</searchLink>; State Key Laboratory of Genetics and Development of Complex Phenotypes, Zhangjiang mRNA Innovation and Translation Center, School of Life Sciences, Fudan University, Shanghai, 200438, PR China. Electronic address: gdren@fudan.edu.cn.<br /><searchLink fieldCode="AU" term="%22Chen+S%22">Chen S</searchLink>; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, PR China; Department of Pharmaceutical Botany, School of Pharmacy, Naval Medical University, Shanghai, 200438, PR China; State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Beijing, 100700, PR China. Electronic address: sschen@shutcm.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%227909578%22">International journal of biological macromolecules</searchLink> [Int J Biol Macromol] 2026 Feb; Vol. 344 (Pt 1), pp. 150467. <i>Date of Electronic Publication: </i>2026 Jan 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>7909578 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-0003 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201418130%22">01418130 </searchLink><i>NLM ISO Abbreviation: </i>Int J Biol Macromol <i>Subsets: </i>MEDLINE
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/j.ijbiomac.2026.150467
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      – Code: eng
        Text: English
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        StartPage: 150467
    Titles:
      – TitleFull: Dual-TERM enables simultaneous profiling of 5' and 3' terminal modifications in small RNAs by integrating enzymatic treatment with PBA-PAGE.
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            NameFull: Yang H
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            NameFull: Zhang B
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            NameFull: Yu X
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            NameFull: Zhang L
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            NameFull: Ren G
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            – D: 01
              M: 02
              Text: 2026 Feb
              Type: published
              Y: 2026
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              Value: 344
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