Therapeutic Potential of Heat Shock Protein 90 Inhibitor 17-DMAG in Regulating METTL3 for Kidney Fibrosis Treatment.

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Title: Therapeutic Potential of Heat Shock Protein 90 Inhibitor 17-DMAG in Regulating METTL3 for Kidney Fibrosis Treatment.
Authors: Lee SM; College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.; Department of Biomedical and Pharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea., Lee MS; Department of Radiology, Seoul National University Boramae Medical Center, Seoul, Republic of Korea., Jung HR; Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Republic of Korea., Lee J; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Cho B; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea., Jin W; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Moon MH; Department of Radiology, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.; Department of Radiology, Seoul National University College of Medicine, Seoul, Republic of Korea., Shin N; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea., Han SH; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea., Choi DS; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea., Lee B; College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.; Department of Biomedical and Pharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea., Hong SP; Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Republic of Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea., Kim JI; Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Republic of Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.; Cancer Research Institute, Seoul National University, Seoul, Republic of Korea., Lim CS; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Cho SY; Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Republic of Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.; Cancer Research Institute, Seoul National University, Seoul, Republic of Korea., Choi JW; College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.; Department of Biomedical and Pharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.; Department of Pharmacology, Institute of Regulatory Innovation Through Science, Kyung Hee University, Seoul, Republic of Korea., Lee JP; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Source: Journal of the American Society of Nephrology : JASN [J Am Soc Nephrol] 2026 Jul 01; Vol. 37 (7), pp. 1404-1422. Date of Electronic Publication: 2026 Jan 26.
Publication Type: Journal Article
Journal Info: Publisher: Wolters Kluwer Health, on behalf of the American Society of Nephrology Country of Publication: United States NLM ID: 9013836 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-3450 (Electronic) Linking ISSN: 10466673 NLM ISO Abbreviation: J Am Soc Nephrol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1533-3450
DOI:10.1681/ASN.0000000975