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Therapeutic Potential of Heat Shock Protein 90 Inhibitor 17-DMAG in Regulating METTL3 for Kidney Fibrosis Treatment.

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Title: Therapeutic Potential of Heat Shock Protein 90 Inhibitor 17-DMAG in Regulating METTL3 for Kidney Fibrosis Treatment.
Authors: Lee SM; College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.; Department of Biomedical and Pharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea., Lee MS; Department of Radiology, Seoul National University Boramae Medical Center, Seoul, Republic of Korea., Jung HR; Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Republic of Korea., Lee J; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Cho B; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea., Jin W; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Moon MH; Department of Radiology, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.; Department of Radiology, Seoul National University College of Medicine, Seoul, Republic of Korea., Shin N; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea., Han SH; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea., Choi DS; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea., Lee B; College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.; Department of Biomedical and Pharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea., Hong SP; Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Republic of Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea., Kim JI; Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Republic of Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.; Cancer Research Institute, Seoul National University, Seoul, Republic of Korea., Lim CS; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Cho SY; Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Republic of Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.; Cancer Research Institute, Seoul National University, Seoul, Republic of Korea., Choi JW; College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.; Department of Biomedical and Pharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.; Department of Pharmacology, Institute of Regulatory Innovation Through Science, Kyung Hee University, Seoul, Republic of Korea., Lee JP; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Source: Journal of the American Society of Nephrology : JASN [J Am Soc Nephrol] 2026 Jul 01; Vol. 37 (7), pp. 1404-1422. Date of Electronic Publication: 2026 Jan 26.
Publication Type: Journal Article
Journal Info: Publisher: Wolters Kluwer Health, on behalf of the American Society of Nephrology Country of Publication: United States NLM ID: 9013836 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-3450 (Electronic) Linking ISSN: 10466673 NLM ISO Abbreviation: J Am Soc Nephrol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Therapeutic Potential of Heat Shock Protein 90 Inhibitor 17-DMAG in Regulating METTL3 for Kidney Fibrosis Treatment.
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  Data: <searchLink fieldCode="AU" term="%22Lee+SM%22">Lee SM</searchLink>; College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.; Department of Biomedical and Pharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+MS%22">Lee MS</searchLink>; Department of Radiology, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jung+HR%22">Jung HR</searchLink>; Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cho+B%22">Cho B</searchLink>; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jin+W%22">Jin W</searchLink>; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Moon+MH%22">Moon MH</searchLink>; Department of Radiology, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.; Department of Radiology, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Shin+N%22">Shin N</searchLink>; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Han+SH%22">Han SH</searchLink>; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+DS%22">Choi DS</searchLink>; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+B%22">Lee B</searchLink>; College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.; Department of Biomedical and Pharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Hong+SP%22">Hong SP</searchLink>; Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Republic of Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JI%22">Kim JI</searchLink>; Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Republic of Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.; Cancer Research Institute, Seoul National University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lim+CS%22">Lim CS</searchLink>; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cho+SY%22">Cho SY</searchLink>; Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Republic of Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.; Cancer Research Institute, Seoul National University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+JW%22">Choi JW</searchLink>; College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.; Department of Biomedical and Pharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.; Department of Pharmacology, Institute of Regulatory Innovation Through Science, Kyung Hee University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JP%22">Lee JP</searchLink>; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
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  Data: <searchLink fieldCode="JN" term="%229013836%22">Journal of the American Society of Nephrology : JASN</searchLink> [J Am Soc Nephrol] 2026 Jul 01; Vol. 37 (7), pp. 1404-1422. <i>Date of Electronic Publication: </i>2026 Jan 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wolters+Kluwer+Health%2C+on+behalf+of+the+American+Society+of+Nephrology%22">Wolters Kluwer Health, on behalf of the American Society of Nephrology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9013836 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1533-3450 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210466673%22">10466673 </searchLink><i>NLM ISO Abbreviation: </i>J Am Soc Nephrol <i>Subsets: </i>MEDLINE
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        Value: 10.1681/ASN.0000000975
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