Mathematical Modeling of Local Drug Delivery in the Oral Cavity: From Release Kinetics to Mini-PBPK and Local PK/PD with Applications to Periodontal Therapies.

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Title: Mathematical Modeling of Local Drug Delivery in the Oral Cavity: From Release Kinetics to Mini-PBPK and Local PK/PD with Applications to Periodontal Therapies.
Authors: Rakoczy R; Department of Chemical and Process Engineering, Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, 70-310 Szczecin, Poland., Machoy-Rakoczy M; Department of Periodontology, Pomeranian Medical University, 70-111 Szczecin, Poland., Gutowska I; Department of Medical Chemistry, Pomeranian Medical University, 70-111 Szczecin, Poland.
Source: Pharmaceutics [Pharmaceutics] 2026 Jan 12; Vol. 18 (1). Date of Electronic Publication: 2026 Jan 12.
Publication Type: Journal Article; Review
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101534003 Publication Model: Electronic Cited Medium: Print ISSN: 1999-4923 (Print) Linking ISSN: 19994923 NLM ISO Abbreviation: Pharmaceutics Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:1999-4923
DOI:10.3390/pharmaceutics18010101