Mathematical Modeling of Local Drug Delivery in the Oral Cavity: From Release Kinetics to Mini-PBPK and Local PK/PD with Applications to Periodontal Therapies.

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Title: Mathematical Modeling of Local Drug Delivery in the Oral Cavity: From Release Kinetics to Mini-PBPK and Local PK/PD with Applications to Periodontal Therapies.
Authors: Rakoczy R; Department of Chemical and Process Engineering, Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, 70-310 Szczecin, Poland., Machoy-Rakoczy M; Department of Periodontology, Pomeranian Medical University, 70-111 Szczecin, Poland., Gutowska I; Department of Medical Chemistry, Pomeranian Medical University, 70-111 Szczecin, Poland.
Source: Pharmaceutics [Pharmaceutics] 2026 Jan 12; Vol. 18 (1). Date of Electronic Publication: 2026 Jan 12.
Publication Type: Journal Article; Review
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101534003 Publication Model: Electronic Cited Medium: Print ISSN: 1999-4923 (Print) Linking ISSN: 19994923 NLM ISO Abbreviation: Pharmaceutics Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Mathematical Modeling of Local Drug Delivery in the Oral Cavity: From Release Kinetics to Mini-PBPK and Local PK/PD with Applications to Periodontal Therapies.
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  Data: <searchLink fieldCode="AU" term="%22Rakoczy+R%22">Rakoczy R</searchLink>; Department of Chemical and Process Engineering, Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, 70-310 Szczecin, Poland.<br /><searchLink fieldCode="AU" term="%22Machoy-Rakoczy+M%22">Machoy-Rakoczy M</searchLink>; Department of Periodontology, Pomeranian Medical University, 70-111 Szczecin, Poland.<br /><searchLink fieldCode="AU" term="%22Gutowska+I%22">Gutowska I</searchLink>; Department of Medical Chemistry, Pomeranian Medical University, 70-111 Szczecin, Poland.
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  Data: <searchLink fieldCode="JN" term="%22101534003%22">Pharmaceutics</searchLink> [Pharmaceutics] 2026 Jan 12; Vol. 18 (1). <i>Date of Electronic Publication: </i>2026 Jan 12.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI%22">MDPI </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101534003 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>1999-4923 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219994923%22">19994923 </searchLink><i>NLM ISO Abbreviation: </i>Pharmaceutics <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.3390/pharmaceutics18010101
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        Text: English
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      – TitleFull: Mathematical Modeling of Local Drug Delivery in the Oral Cavity: From Release Kinetics to Mini-PBPK and Local PK/PD with Applications to Periodontal Therapies.
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              Text: 2026 Jan 12
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              Y: 2026
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