SARS-CoV-2 evolution enhances endocytic uptake while preserving TMPRSS2-dependent fusion.

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Title: SARS-CoV-2 evolution enhances endocytic uptake while preserving TMPRSS2-dependent fusion.
Authors: Magnus CL; Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, Regensburg, Germany., Jaber ZH; Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, Regensburg, Germany., Hiergeist A; Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany., Arnold L; Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, Regensburg, Germany., Marchel H; Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany., Lamprecht A; Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany., Hanses F; Emergency Department, University Hospital Regensburg, Regensburg, Germany.; Department of Infection Prevention and Infectious Diseases, University Hospital Regensburg, Regensburg, Germany., Dienemann T; Department of Surgery, University Hospital Regensburg, Regensburg, Germany., Schneckenpointner R; Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany., Lubnow M; Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany., Müller T; Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany., Lunz D; Department of Anesthesiology, University Hospital Regensburg, Regensburg, Germany., Hitzenbichler F; Department of Infection Prevention and Infectious Diseases, University Hospital Regensburg, Regensburg, Germany., Schmid S; Department of Internal Medicine I, University Hospital Regensburg, Regensburg, Germany., Müller M; Department of Internal Medicine I, University Hospital Regensburg, Regensburg, Germany., Poeck H; Department of Department of Internal Medicine 3, University Medical Center, Regensburg, Germany.; Leibniz Institute for Immunotherapy, Regensburg, Germany., Graf B; Department of Anesthesiology, University Hospital Regensburg, Regensburg, Germany., Salzberger B; Department of Infection Prevention and Infectious Diseases, University Hospital Regensburg, Regensburg, Germany., Gessner A; Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, Regensburg, Germany.; Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany., Schmidt B; Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, Regensburg, Germany.; Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany., Schuster P; Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany.
Source: Frontiers in immunology [Front Immunol] 2026 Jan 12; Vol. 16, pp. 1736891. Date of Electronic Publication: 2026 Jan 12 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: SARS-CoV-2 evolution enhances endocytic uptake while preserving TMPRSS2-dependent fusion.
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  Data: <searchLink fieldCode="AU" term="%22Magnus+CL%22">Magnus CL</searchLink>; Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Jaber+ZH%22">Jaber ZH</searchLink>; Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hiergeist+A%22">Hiergeist A</searchLink>; Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Arnold+L%22">Arnold L</searchLink>; Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Marchel+H%22">Marchel H</searchLink>; Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Lamprecht+A%22">Lamprecht A</searchLink>; Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hanses+F%22">Hanses F</searchLink>; Emergency Department, University Hospital Regensburg, Regensburg, Germany.; Department of Infection Prevention and Infectious Diseases, University Hospital Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Dienemann+T%22">Dienemann T</searchLink>; Department of Surgery, University Hospital Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schneckenpointner+R%22">Schneckenpointner R</searchLink>; Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Lubnow+M%22">Lubnow M</searchLink>; Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Müller+T%22">Müller T</searchLink>; Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Lunz+D%22">Lunz D</searchLink>; Department of Anesthesiology, University Hospital Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hitzenbichler+F%22">Hitzenbichler F</searchLink>; Department of Infection Prevention and Infectious Diseases, University Hospital Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schmid+S%22">Schmid S</searchLink>; Department of Internal Medicine I, University Hospital Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Müller+M%22">Müller M</searchLink>; Department of Internal Medicine I, University Hospital Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Poeck+H%22">Poeck H</searchLink>; Department of Department of Internal Medicine 3, University Medical Center, Regensburg, Germany.; Leibniz Institute for Immunotherapy, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Graf+B%22">Graf B</searchLink>; Department of Anesthesiology, University Hospital Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Salzberger+B%22">Salzberger B</searchLink>; Department of Infection Prevention and Infectious Diseases, University Hospital Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Gessner+A%22">Gessner A</searchLink>; Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, Regensburg, Germany.; Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schmidt+B%22">Schmidt B</searchLink>; Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, Regensburg, Germany.; Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schuster+P%22">Schuster P</searchLink>; Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Jan 12; Vol. 16, pp. 1736891. <i>Date of Electronic Publication: </i>2026 Jan 12 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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