Selective blockade of latent TGF-β1 activation suppresses tissue fibrosis with good safety.
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| Title: | Selective blockade of latent TGF-β1 activation suppresses tissue fibrosis with good safety. |
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| Authors: | Kanamori M; Research Division, Chugai Pharmaceutical Co. Ltd., Yokohama, Kanagawa, Japan., Sato I; Research Division, Chugai Pharmaceutical Co. Ltd., Yokohama, Kanagawa, Japan., Koo CX; Chugai Pharmabody Research Pte. Ltd., Singapore, Singapore.; Health Sciences Authority, Singapore, Singapore., Sun Y; Chugai Pharmabody Research Pte. Ltd., Singapore, Singapore., Kawauchi H; Research Division, Chugai Pharmaceutical Co. Ltd., Yokohama, Kanagawa, Japan., Nakagawa K; Research Division, Chugai Pharmaceutical Co. Ltd., Yokohama, Kanagawa, Japan., Murai A; Translational Research Division, Chugai Pharmaceutical Co. Ltd., Yokohama, Kanagawa, Japan., Asanuma K; Translational Research Division, Chugai Pharmaceutical Co. Ltd., Yokohama, Kanagawa, Japan., Gan SW; Chugai Pharmabody Research Pte. Ltd., Singapore, Singapore., Pang CL; Chugai Pharmabody Research Pte. Ltd., Singapore, Singapore.; AbbVie Operations Singapore Pte. Ltd., Singapore, Singapore., Shimizu Y; Research Division, Chugai Pharmaceutical Co. Ltd., Yokohama, Kanagawa, Japan., Shida-Kawazoe M; Research Division, Chugai Pharmaceutical Co. Ltd., Yokohama, Kanagawa, Japan., Kanamaru C; Translational Research Division, Chugai Pharmaceutical Co. Ltd., Yokohama, Kanagawa, Japan., Kayukawa Y; Research Division, Chugai Pharmaceutical Co. Ltd., Yokohama, Kanagawa, Japan., Hada N; Research Division, Chugai Pharmaceutical Co. Ltd., Yokohama, Kanagawa, Japan., Ohmine K; Translational Research Division, Chugai Pharmaceutical Co. Ltd., Yokohama, Kanagawa, Japan., Kitazawa T; Research Division, Chugai Pharmaceutical Co. Ltd., Yokohama, Kanagawa, Japan., Nezu J; Research Division, Chugai Pharmaceutical Co. Ltd., Yokohama, Kanagawa, Japan.; Mochida Pharmaceutical Co., Ltd., Gotemba, Shizuoka, Japan., Igawa T; Research Division, Chugai Pharmaceutical Co. Ltd., Yokohama, Kanagawa, Japan., Shimada H; Research Division, Chugai Pharmaceutical Co. Ltd., Yokohama, Kanagawa, Japan. shimada.hideaki12@chugai-pharm.co.jp.; Chugai Pharmabody Research Pte. Ltd., Singapore, Singapore. shimada.hideaki12@chugai-pharm.co.jp. |
| Source: | Communications medicine [Commun Med (Lond)] 2026 Jan 28; Vol. 6 (1). Date of Electronic Publication: 2026 Jan 28. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Portfolio Country of Publication: England NLM ID: 9918250414506676 Publication Model: Electronic Cited Medium: Internet ISSN: 2730-664X (Electronic) Linking ISSN: 2730664X NLM ISO Abbreviation: Commun Med (Lond) Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2730-664X |
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| DOI: | 10.1038/s43856-026-01408-w |
