Five dominant amino acid substitution signatures shape tumour immunity.

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Title: Five dominant amino acid substitution signatures shape tumour immunity.
Authors: Juhász S; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary. juhasz.szilvia@brc.hu.; Cancer Microbiome Research Group, HCEMM, Szeged, Hungary. juhasz.szilvia@brc.hu., Papp BT; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.; HCEMM-BRC Systems Immunology Research Group, Szeged, Hungary.; Department of Dermatology and Allergology, University of Szeged, Szeged, Hungary., Fülöp AT; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.; HCEMM-BRC Systems Immunology Research Group, Szeged, Hungary.; National Academy of Scientist Education, Szeged, Hungary.; Doctoral School of Biology, University of Szeged, Szeged, Hungary., Farkas Z; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary., Kókai D; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.; HCEMM-BRC Systems Immunology Research Group, Szeged, Hungary., Gyémánt DA; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.; HCEMM-BRC Systems Immunology Research Group, Szeged, Hungary.; National Academy of Scientist Education, Szeged, Hungary., Tóth F; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.; HCEMM-BRC Systems Immunology Research Group, Szeged, Hungary.; Doctoral School of Biology, University of Szeged, Szeged, Hungary., Nacsa Z; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary., Spekhardt D; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary., Koncz B; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.; HCEMM-BRC Systems Immunology Research Group, Szeged, Hungary., Burkovics P; Institute of Genetics, HUN-REN Biological Research Centre, Szeged, Hungary., Pál C; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary. cpal@brc.hu., Manczinger M; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary. manczinger.mate@brc.hu.; HCEMM-BRC Systems Immunology Research Group, Szeged, Hungary. manczinger.mate@brc.hu.; Department of Dermatology and Allergology, University of Szeged, Szeged, Hungary. manczinger.mate@brc.hu.
Source: Molecular systems biology [Mol Syst Biol] 2026 May; Vol. 22 (5), pp. 766-786. Date of Electronic Publication: 2026 Jan 28.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101235389 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-4292 (Electronic) Linking ISSN: 17444292 NLM ISO Abbreviation: Mol Syst Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1744-4292
DOI:10.1038/s44320-026-00193-x