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Five dominant amino acid substitution signatures shape tumour immunity.

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Title: Five dominant amino acid substitution signatures shape tumour immunity.
Authors: Juhász S; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary. juhasz.szilvia@brc.hu.; Cancer Microbiome Research Group, HCEMM, Szeged, Hungary. juhasz.szilvia@brc.hu., Papp BT; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.; HCEMM-BRC Systems Immunology Research Group, Szeged, Hungary.; Department of Dermatology and Allergology, University of Szeged, Szeged, Hungary., Fülöp AT; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.; HCEMM-BRC Systems Immunology Research Group, Szeged, Hungary.; National Academy of Scientist Education, Szeged, Hungary.; Doctoral School of Biology, University of Szeged, Szeged, Hungary., Farkas Z; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary., Kókai D; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.; HCEMM-BRC Systems Immunology Research Group, Szeged, Hungary., Gyémánt DA; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.; HCEMM-BRC Systems Immunology Research Group, Szeged, Hungary.; National Academy of Scientist Education, Szeged, Hungary., Tóth F; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.; HCEMM-BRC Systems Immunology Research Group, Szeged, Hungary.; Doctoral School of Biology, University of Szeged, Szeged, Hungary., Nacsa Z; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary., Spekhardt D; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary., Koncz B; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.; HCEMM-BRC Systems Immunology Research Group, Szeged, Hungary., Burkovics P; Institute of Genetics, HUN-REN Biological Research Centre, Szeged, Hungary., Pál C; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary. cpal@brc.hu., Manczinger M; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary. manczinger.mate@brc.hu.; HCEMM-BRC Systems Immunology Research Group, Szeged, Hungary. manczinger.mate@brc.hu.; Department of Dermatology and Allergology, University of Szeged, Szeged, Hungary. manczinger.mate@brc.hu.
Source: Molecular systems biology [Mol Syst Biol] 2026 May; Vol. 22 (5), pp. 766-786. Date of Electronic Publication: 2026 Jan 28.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101235389 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-4292 (Electronic) Linking ISSN: 17444292 NLM ISO Abbreviation: Mol Syst Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Five dominant amino acid substitution signatures shape tumour immunity.
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  Data: <searchLink fieldCode="AU" term="%22Juhász+S%22">Juhász S</searchLink>; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary. juhasz.szilvia@brc.hu.; Cancer Microbiome Research Group, HCEMM, Szeged, Hungary. juhasz.szilvia@brc.hu.<br /><searchLink fieldCode="AU" term="%22Papp+BT%22">Papp BT</searchLink>; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.; HCEMM-BRC Systems Immunology Research Group, Szeged, Hungary.; Department of Dermatology and Allergology, University of Szeged, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Fülöp+AT%22">Fülöp AT</searchLink>; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.; HCEMM-BRC Systems Immunology Research Group, Szeged, Hungary.; National Academy of Scientist Education, Szeged, Hungary.; Doctoral School of Biology, University of Szeged, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Farkas+Z%22">Farkas Z</searchLink>; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Kókai+D%22">Kókai D</searchLink>; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.; HCEMM-BRC Systems Immunology Research Group, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Gyémánt+DA%22">Gyémánt DA</searchLink>; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.; HCEMM-BRC Systems Immunology Research Group, Szeged, Hungary.; National Academy of Scientist Education, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Tóth+F%22">Tóth F</searchLink>; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.; HCEMM-BRC Systems Immunology Research Group, Szeged, Hungary.; Doctoral School of Biology, University of Szeged, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Nacsa+Z%22">Nacsa Z</searchLink>; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Spekhardt+D%22">Spekhardt D</searchLink>; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Koncz+B%22">Koncz B</searchLink>; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary.; HCEMM-BRC Systems Immunology Research Group, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Burkovics+P%22">Burkovics P</searchLink>; Institute of Genetics, HUN-REN Biological Research Centre, Szeged, Hungary.<br /><searchLink fieldCode="AU" term="%22Pál+C%22">Pál C</searchLink>; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary. cpal@brc.hu.<br /><searchLink fieldCode="AU" term="%22Manczinger+M%22">Manczinger M</searchLink>; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary. manczinger.mate@brc.hu.; HCEMM-BRC Systems Immunology Research Group, Szeged, Hungary. manczinger.mate@brc.hu.; Department of Dermatology and Allergology, University of Szeged, Szeged, Hungary. manczinger.mate@brc.hu.
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