C2α-carbanion-protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2-hydroxyacyl-CoA lyase.
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| Title: | C2α-carbanion-protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2-hydroxyacyl-CoA lyase. |
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| Authors: | Zahn M; Centre for Enzyme Innovation, School of the Environment and Life Sciences, University of Portsmouth, UK.; Core Facility Protein Production, Biozentrum, Martin-Luther-University-Halle-Wittenberg, Germany., Seroka B; Faculty of Chemistry, University of Bialystok, Poland., Lazny R; Faculty of Chemistry, University of Bialystok, Poland., Lotowski Z; Faculty of Chemistry, University of Bialystok, Poland., Rohwerder T; Department of Microbial Biotechnology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany. |
| Source: | FEBS open bio [FEBS Open Bio] 2026 Jul; Vol. 16 (7), pp. 1314-1327. Date of Electronic Publication: 2026 Jan 28. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 101580716 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-5463 (Electronic) Linking ISSN: 22115463 NLM ISO Abbreviation: FEBS Open Bio Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2211-5463 |
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| DOI: | 10.1002/2211-5463.70199 |