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The emerging role of fatty acids as key bioactive components of Ganoderma lucidum spore oil in alleviating tumor progression.

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Title: The emerging role of fatty acids as key bioactive components of Ganoderma lucidum spore oil in alleviating tumor progression.
Authors: Chen QJ; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China., Li ZX; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China., Wang GC; Guangzhou HanFang Pharmaceutical Company Limited/National Engineering Research Center of Pharmaceutical Processing Technology of Traditional Chinese Medicine and Drug Innovation/Guangdong Provincial Key Laboratory of Medicinal Lipids, Guangzhou, 510240, China., Xie T; School of Chinese Materia Medica and Yunnan Key Laboratory of Southern Medicinal Utilization, Yunnan University of Traditional Chinese Medicine, Kunming, 650500, China., Xiao GD; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China., Xu H; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China., Li J; Guangzhou HanFang Pharmaceutical Company Limited/National Engineering Research Center of Pharmaceutical Processing Technology of Traditional Chinese Medicine and Drug Innovation/Guangdong Provincial Key Laboratory of Medicinal Lipids, Guangzhou, 510240, China., Luo X; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China., Li YF; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China., Liang L; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China., Liu JY; Guangzhou HanFang Pharmaceutical Company Limited/National Engineering Research Center of Pharmaceutical Processing Technology of Traditional Chinese Medicine and Drug Innovation/Guangdong Provincial Key Laboratory of Medicinal Lipids, Guangzhou, 510240, China. maoyk@byshf.com., Wu YP; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China. wuyanping@jnu.edu.cn., He RR; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China. rongronghe@jnu.edu.cn.; School of Chinese Materia Medica and Yunnan Key Laboratory of Southern Medicinal Utilization, Yunnan University of Traditional Chinese Medicine, Kunming, 650500, China. rongronghe@jnu.edu.cn.; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, 999078, China. rongronghe@jnu.edu.cn.
Source: Journal of natural medicines [J Nat Med] 2026 Mar; Vol. 80 (2), pp. 269-287. Date of Electronic Publication: 2026 Jan 28.
Publication Type: Journal Article; Review
Journal Info: Publisher: Springer Country of Publication: Japan NLM ID: 101518405 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1861-0293 (Electronic) Linking ISSN: 13403443 NLM ISO Abbreviation: J Nat Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1861-0293
DOI:10.1007/s11418-025-01984-6