The emerging role of fatty acids as key bioactive components of Ganoderma lucidum spore oil in alleviating tumor progression.

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Title: The emerging role of fatty acids as key bioactive components of Ganoderma lucidum spore oil in alleviating tumor progression.
Authors: Chen QJ; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China., Li ZX; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China., Wang GC; Guangzhou HanFang Pharmaceutical Company Limited/National Engineering Research Center of Pharmaceutical Processing Technology of Traditional Chinese Medicine and Drug Innovation/Guangdong Provincial Key Laboratory of Medicinal Lipids, Guangzhou, 510240, China., Xie T; School of Chinese Materia Medica and Yunnan Key Laboratory of Southern Medicinal Utilization, Yunnan University of Traditional Chinese Medicine, Kunming, 650500, China., Xiao GD; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China., Xu H; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China., Li J; Guangzhou HanFang Pharmaceutical Company Limited/National Engineering Research Center of Pharmaceutical Processing Technology of Traditional Chinese Medicine and Drug Innovation/Guangdong Provincial Key Laboratory of Medicinal Lipids, Guangzhou, 510240, China., Luo X; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China., Li YF; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China., Liang L; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China., Liu JY; Guangzhou HanFang Pharmaceutical Company Limited/National Engineering Research Center of Pharmaceutical Processing Technology of Traditional Chinese Medicine and Drug Innovation/Guangdong Provincial Key Laboratory of Medicinal Lipids, Guangzhou, 510240, China. maoyk@byshf.com., Wu YP; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China. wuyanping@jnu.edu.cn., He RR; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China. rongronghe@jnu.edu.cn.; School of Chinese Materia Medica and Yunnan Key Laboratory of Southern Medicinal Utilization, Yunnan University of Traditional Chinese Medicine, Kunming, 650500, China. rongronghe@jnu.edu.cn.; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, 999078, China. rongronghe@jnu.edu.cn.
Source: Journal of natural medicines [J Nat Med] 2026 Mar; Vol. 80 (2), pp. 269-287. Date of Electronic Publication: 2026 Jan 28.
Publication Type: Journal Article; Review
Journal Info: Publisher: Springer Country of Publication: Japan NLM ID: 101518405 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1861-0293 (Electronic) Linking ISSN: 13403443 NLM ISO Abbreviation: J Nat Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The emerging role of fatty acids as key bioactive components of Ganoderma lucidum spore oil in alleviating tumor progression.
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  Data: <searchLink fieldCode="AU" term="%22Chen+QJ%22">Chen QJ</searchLink>; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China.<br /><searchLink fieldCode="AU" term="%22Li+ZX%22">Li ZX</searchLink>; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China.<br /><searchLink fieldCode="AU" term="%22Wang+GC%22">Wang GC</searchLink>; Guangzhou HanFang Pharmaceutical Company Limited/National Engineering Research Center of Pharmaceutical Processing Technology of Traditional Chinese Medicine and Drug Innovation/Guangdong Provincial Key Laboratory of Medicinal Lipids, Guangzhou, 510240, China.<br /><searchLink fieldCode="AU" term="%22Xie+T%22">Xie T</searchLink>; School of Chinese Materia Medica and Yunnan Key Laboratory of Southern Medicinal Utilization, Yunnan University of Traditional Chinese Medicine, Kunming, 650500, China.<br /><searchLink fieldCode="AU" term="%22Xiao+GD%22">Xiao GD</searchLink>; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China.<br /><searchLink fieldCode="AU" term="%22Xu+H%22">Xu H</searchLink>; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Guangzhou HanFang Pharmaceutical Company Limited/National Engineering Research Center of Pharmaceutical Processing Technology of Traditional Chinese Medicine and Drug Innovation/Guangdong Provincial Key Laboratory of Medicinal Lipids, Guangzhou, 510240, China.<br /><searchLink fieldCode="AU" term="%22Luo+X%22">Luo X</searchLink>; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China.<br /><searchLink fieldCode="AU" term="%22Li+YF%22">Li YF</searchLink>; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China.<br /><searchLink fieldCode="AU" term="%22Liang+L%22">Liang L</searchLink>; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China.<br /><searchLink fieldCode="AU" term="%22Liu+JY%22">Liu JY</searchLink>; Guangzhou HanFang Pharmaceutical Company Limited/National Engineering Research Center of Pharmaceutical Processing Technology of Traditional Chinese Medicine and Drug Innovation/Guangdong Provincial Key Laboratory of Medicinal Lipids, Guangzhou, 510240, China. maoyk@byshf.com.<br /><searchLink fieldCode="AU" term="%22Wu+YP%22">Wu YP</searchLink>; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China. wuyanping@jnu.edu.cn.<br /><searchLink fieldCode="AU" term="%22He+RR%22">He RR</searchLink>; State Key Laboratory of Bioactive Molecules and Druggability Assessment/Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs/Guangdong Engineering Research Center of Traditional Chinese Medicine & Disease Susceptibility/The First Affiliated Hospital/The Sixth Affiliated Hospital/Guangdong Second Provincial General Hospital/Guangdong Engineering Research Center of Traditional Chinese Medicine & Health Products/International Cooperative Laboratory of TC Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE)/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/College of Pharmacy/School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China. rongronghe@jnu.edu.cn.; School of Chinese Materia Medica and Yunnan Key Laboratory of Southern Medicinal Utilization, Yunnan University of Traditional Chinese Medicine, Kunming, 650500, China. rongronghe@jnu.edu.cn.; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, 999078, China. rongronghe@jnu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101518405%22">Journal of natural medicines</searchLink> [J Nat Med] 2026 Mar; Vol. 80 (2), pp. 269-287. <i>Date of Electronic Publication: </i>2026 Jan 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Japan <i>NLM ID: </i>101518405 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1861-0293 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213403443%22">13403443 </searchLink><i>NLM ISO Abbreviation: </i>J Nat Med <i>Subsets: </i>MEDLINE
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