Targeting the Membrane-Embedded Rhomboid Protease GlpG: A Multimodal Strategy for Inhibitor Discovery and Mechanistic Insight.
Saved in:
| Title: | Targeting the Membrane-Embedded Rhomboid Protease GlpG: A Multimodal Strategy for Inhibitor Discovery and Mechanistic Insight. |
|---|---|
| Authors: | Bohg C; Research Unit Molecular Biophysics, Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany., Dubanych Y; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czech Republic.; Faculty of Food and Biochemical Technology, University of Chemistry and Technology, Prague, Czech Republic., Kosteletos S; Research Unit Molecular Biophysics, Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany., Xiao T; Research Unit Molecular Biophysics, Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany., Neuenschwander M; Core Facility Screening Unit, Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany., Utesch T; Research Unit Structural Chemistry & Computational Biophysics, Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany., Lisurek M; Research Unit Structural Chemistry & Computational Biophysics, Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany., Öster C; Research Unit Molecular Biophysics, Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany., Oder A; Core Facility Screening Unit, Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany., Seyffarth C; Core Facility Screening Unit, Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany., Bach K; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czech Republic., Leone DG; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czech Republic., Filandr F; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czech Republic., Wegert M; Research Unit Biomolecule Modification and Delivery, Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany., Lange S; Research Unit Molecular Biophysics, Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany., Sawczyc H; Research Unit Molecular Biophysics, Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany., von Kries JP; Core Facility Screening Unit, Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany., Hackenberger CPR; Research Unit Biomolecule Modification and Delivery, Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany.; Institute of Chemistry, Humboldt-Universität zu Berlin, Berlin, Germany., Specker E; Core Facility Compound Management, Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany., Sun H; Research Unit Structural Chemistry & Computational Biophysics, Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany.; Institute of Chemistry, Technische Universität Berlin, Berlin, Germany., Stříšovský K; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czech Republic., Lange A; Research Unit Molecular Biophysics, Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany.; Institute of Biology, Humboldt-Universität zu Berlin, Berlin, Germany. |
| Source: | Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2026 Mar 02; Vol. 65 (10), pp. e14067. Date of Electronic Publication: 2026 Jan 28. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
Be the first to leave a comment!
