Cost-utility-analysis of molecular-integrated-profile for women with (high)intermediate risk endometrial cancer - PORTEC-4a an international, randomised, phase 3 trial.

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Title: Cost-utility-analysis of molecular-integrated-profile for women with (high)intermediate risk endometrial cancer - PORTEC-4a an international, randomised, phase 3 trial.
Authors: van den Heerik ASVM; Department of Radiation Oncology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address: a.v.m.van_den_heerik@lumc.nl., Horeweg N; Department of Radiation Oncology, Leiden University Medical Center, Leiden, The Netherlands., Haverkort MAD; Department of Radiation Oncology, Radiotherapiegroep, Arnhem, The Netherlands., Kuijsters N; Maastro, Maastricht, The Netherlands., Kommoss S; Department of Women's Health, Tübingen University Hospital, Tübingen and Diak Klinikum, Department of Gynecology & Obstetrics, Schwaebisch Hall, Germany., Koppe FLA; Institute Verbeeten, Tilburg, The Netherlands., Nowee ME; Department of Radiotherapy, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Westerveld H; Department of Radiation Oncology, Amsterdam University Medical Centers, University of Amsterdam, The Netherlands; Department of Radiotherapy, Erasmus MC - Cancer Institute, University of Rotterdam, Rotterdam, The Netherlands., de Jong MAA; Radiotherapeutisch Instituut Friesland, Leeuwarden, The Netherlands., Frühauf F; Department of Gynaecology, Obstetrics and Neonatology, General University Hospital Prague, First Medical Faculty of the Charles University, Czech Republic., Cnossen JS; Department of Radiotherapy, Catharina Hospital Eindhoven, The Netherlands., Mens JWM; Department of Radiotherapy, Erasmus MC - Cancer Institute, University of Rotterdam, Rotterdam, The Netherlands., Beukema JC; Department of Radiotherapy, University Medical Center Groningen, Groningen, The Netherlands., Chargari C; Department of Radiotherapy, Institut Gustave Roussy, Villejuif, France., Gillham C; Department of Radiation Oncology, St. Luke's Hospital, Dublin, Ireland and Caner Trials Ireland, Ireland., Tseng DSJ; Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, The Netherlands., Vandecasteele K; Department of Radiation Oncology, Ghent University Hospital, Ghent, Belgium., Hamann M; Department of Gynecology, Rotkreuzklinikum München, Germany., Kiderlen M; Department of Radiation Oncology, Haaglanden Medisch Centrum, Leidschendam, The Netherlands., Polterauer S; Department of Obstetrics and Gynaecology, University Hospital Vienna, Vienna, Austria., Staebler A; Institute of Pathology and Neuropathology, University Hospital of Tübingen, Tübingen, Germany., Nijman HW; Department of Gynecology, University Medical Center Groningen, Groningen, The Netherlands., Wortman BG; Department of Radiation Oncology, Leiden University Medical Center, Leiden, The Netherlands; Department of Radiotherapy, Catharina Hospital Eindhoven, The Netherlands., De Boer SM; Department of Radiation Oncology, Leiden University Medical Center, Leiden, The Netherlands., Verhoeven-Adema KW; Netherlands Comprehensive Cancer Organisation, Utrecht, The Netherlands., Nout RA; Department of Radiation Oncology, Leiden University Medical Center, Leiden, The Netherlands; Department of Radiotherapy, Erasmus MC - Cancer Institute, University of Rotterdam, Rotterdam, The Netherlands., Putter H; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands., Smit VTHBM; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands., Creutzberg CL; Department of Radiation Oncology, Leiden University Medical Center, Leiden, The Netherlands., van den Hout WB; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.
Source: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology [Radiother Oncol] 2026 Apr; Vol. 217, pp. 111406. Date of Electronic Publication: 2026 Jan 30.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III; Multicenter Study
Journal Info: Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8407192 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0887 (Electronic) Linking ISSN: 01678140 NLM ISO Abbreviation: Radiother Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-0887
DOI:10.1016/j.radonc.2026.111406