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Pharmacokinetic Evaluation of a Cinnamon Product on CYP2A6 Substrate Drugs: Application of a Novel Tool Involving the Nicotine Metabolite Ratio.

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Title: Pharmacokinetic Evaluation of a Cinnamon Product on CYP2A6 Substrate Drugs: Application of a Novel Tool Involving the Nicotine Metabolite Ratio.
Authors: Nguyen AP; College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, WA, USA., Hadi DL; College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, WA, USA.; Center of Excellence for Natural Product Drug Interaction Research, Spokane, WA, USA., Todd DA; Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina, USA., Manwill PK; Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina, USA., White JR; College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, WA, USA., Layton ME; Elson S. Floyd College of Medicine, Washington State University, Spokane, WA, USA., Cech NB; Center of Excellence for Natural Product Drug Interaction Research, Spokane, WA, USA.; Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina, USA., Thummel KE; Center of Excellence for Natural Product Drug Interaction Research, Spokane, WA, USA.; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA, USA., Paine MF; College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, WA, USA.; Center of Excellence for Natural Product Drug Interaction Research, Spokane, WA, USA.
Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2026 Jun; Vol. 119 (6), pp. 1485-1493. Date of Electronic Publication: 2026 Feb 01.
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Nguyen+AP%22">Nguyen AP</searchLink>; College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, WA, USA.<br /><searchLink fieldCode="AU" term="%22Hadi+DL%22">Hadi DL</searchLink>; College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, WA, USA.; Center of Excellence for Natural Product Drug Interaction Research, Spokane, WA, USA.<br /><searchLink fieldCode="AU" term="%22Todd+DA%22">Todd DA</searchLink>; Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Manwill+PK%22">Manwill PK</searchLink>; Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22White+JR%22">White JR</searchLink>; College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, WA, USA.<br /><searchLink fieldCode="AU" term="%22Layton+ME%22">Layton ME</searchLink>; Elson S. Floyd College of Medicine, Washington State University, Spokane, WA, USA.<br /><searchLink fieldCode="AU" term="%22Cech+NB%22">Cech NB</searchLink>; Center of Excellence for Natural Product Drug Interaction Research, Spokane, WA, USA.; Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Thummel+KE%22">Thummel KE</searchLink>; Center of Excellence for Natural Product Drug Interaction Research, Spokane, WA, USA.; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Paine+MF%22">Paine MF</searchLink>; College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, WA, USA.; Center of Excellence for Natural Product Drug Interaction Research, Spokane, WA, USA.
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        Value: 10.1002/cpt.70218
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      – TitleFull: Pharmacokinetic Evaluation of a Cinnamon Product on CYP2A6 Substrate Drugs: Application of a Novel Tool Involving the Nicotine Metabolite Ratio.
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              Text: 2026 Jun
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