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Elevating Circulating L-Kynurenine Promotes Frailty in Aging Mice.

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Title: Elevating Circulating L-Kynurenine Promotes Frailty in Aging Mice.
Authors: Kawaida MY; Department of Applied Physiology and Kinesiology, The University of Florida, Gainesville, Florida, USA., Tice AL; Department of Applied Physiology and Kinesiology, The University of Florida, Gainesville, Florida, USA., Alvarez S; Department of Applied Physiology and Kinesiology, The University of Florida, Gainesville, Florida, USA., Lackey JA; Department of Applied Physiology and Kinesiology, The University of Florida, Gainesville, Florida, USA., Izaguirre B; Department of Applied Physiology and Kinesiology, The University of Florida, Gainesville, Florida, USA., Yang Q; Department of Applied Physiology and Kinesiology, The University of Florida, Gainesville, Florida, USA., Wei-LaPierre L; Department of Applied Physiology and Kinesiology, The University of Florida, Gainesville, Florida, USA.; Center for Exercise Science, The University of Florida, Gainesville, Florida, USA.; Myology Institute, The University of Florida, Gainesville, Florida, USA., Hepple RT; Myology Institute, The University of Florida, Gainesville, Florida, USA.; Department of Physical Therapy, The University of Florida, Gainesville, Florida, USA., Ryan TE; Department of Applied Physiology and Kinesiology, The University of Florida, Gainesville, Florida, USA.; Center for Exercise Science, The University of Florida, Gainesville, Florida, USA.; Myology Institute, The University of Florida, Gainesville, Florida, USA.
Source: Journal of cachexia, sarcopenia and muscle [J Cachexia Sarcopenia Muscle] 2026 Feb; Vol. 17 (1), pp. e70214.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons Ltd on behalf of Society on Sarcopenia, Cachexia and Wasting Disorders Country of Publication: Germany NLM ID: 101552883 Publication Model: Print Cited Medium: Internet ISSN: 2190-6009 (Electronic) Linking ISSN: 21905991 NLM ISO Abbreviation: J Cachexia Sarcopenia Muscle Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Elevating Circulating L-Kynurenine Promotes Frailty in Aging Mice.
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  Data: <searchLink fieldCode="AU" term="%22Kawaida+MY%22">Kawaida MY</searchLink>; Department of Applied Physiology and Kinesiology, The University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Tice+AL%22">Tice AL</searchLink>; Department of Applied Physiology and Kinesiology, The University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Alvarez+S%22">Alvarez S</searchLink>; Department of Applied Physiology and Kinesiology, The University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Lackey+JA%22">Lackey JA</searchLink>; Department of Applied Physiology and Kinesiology, The University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Izaguirre+B%22">Izaguirre B</searchLink>; Department of Applied Physiology and Kinesiology, The University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Yang+Q%22">Yang Q</searchLink>; Department of Applied Physiology and Kinesiology, The University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Wei-LaPierre+L%22">Wei-LaPierre L</searchLink>; Department of Applied Physiology and Kinesiology, The University of Florida, Gainesville, Florida, USA.; Center for Exercise Science, The University of Florida, Gainesville, Florida, USA.; Myology Institute, The University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Hepple+RT%22">Hepple RT</searchLink>; Myology Institute, The University of Florida, Gainesville, Florida, USA.; Department of Physical Therapy, The University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Ryan+TE%22">Ryan TE</searchLink>; Department of Applied Physiology and Kinesiology, The University of Florida, Gainesville, Florida, USA.; Center for Exercise Science, The University of Florida, Gainesville, Florida, USA.; Myology Institute, The University of Florida, Gainesville, Florida, USA.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons+Ltd+on+behalf+of+Society+on+Sarcopenia%2C+Cachexia+and+Wasting+Disorders%22">John Wiley & Sons Ltd on behalf of Society on Sarcopenia, Cachexia and Wasting Disorders </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101552883 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2190-6009 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221905991%22">21905991 </searchLink><i>NLM ISO Abbreviation: </i>J Cachexia Sarcopenia Muscle <i>Subsets: </i>MEDLINE
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        Value: 10.1002/jcsm.70214
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        Text: English
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              Text: 2026 Feb
              Type: published
              Y: 2026
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