Polygonum barbatum extract induces ER stress-mediated UPR and autophagy to suppress colorectal cancer growth.

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Title: Polygonum barbatum extract induces ER stress-mediated UPR and autophagy to suppress colorectal cancer growth.
Authors: Chang PK; Graduate Institute of Medical Sciences, National Defense Medical University, NO. 161, Sec. 6, Minquan E. Rd., Neihu District, Taipei City 11490, Taiwan (R.O.C.).; Division of Colon and Rectal Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical University, No. 325, Sec. 2, Chenggong Rd., Neihu District, Taipei City 11490, Taiwan (R.O.C).; School of Medicine, National Defense Medical University, No. 161, Sec. 6, Minquan E. Rd., Neihu Dist., Taipei City 11490, Taiwan (R.O.C.)., Yen IC; School of Pharmacy, National Defense Medical University, No. 161, Sec. 6, Minquan E. Rd., Neihu Dist., Taipei City 11490, Taiwan (R.O.C.)., Tsai WC; Graduate Institute of Aerospace and Undersea Medicine, National Defense Medical University, No. 161, Sec. 6, Minquan E. Rd., Neihu Dist., Taipei City 11490, Taiwan (R.O.C.)., Lin KT; Department of Radiation Oncology, Cardinal Tien Hospital, No. 362, Zhongzheng Rd., Xindian Dist., New Taipei City 23148, Taiwan (R.O.C.); and School of Medicine, College of Medicine, Fu -Jen Catholic University, No. 510, Zhongzheng Rd., Xinzhuang Dist., New Taipei City 242062, Taiwan (R.O.C.)., Lee SY; Graduate Institute of Medical Sciences, National Defense Medical University, NO. 161, Sec. 6, Minquan E. Rd., Neihu District, Taipei City 11490, Taiwan (R.O.C.).; Graduate Institute of Aerospace and Undersea Medicine, National Defense Medical University, No. 161, Sec. 6, Minquan E. Rd., Neihu Dist., Taipei City 11490, Taiwan (R.O.C.).
Source: Toxicology research [Toxicol Res (Camb)] 2026 Jan 29; Vol. 15 (1), pp. tfaf188. Date of Electronic Publication: 2026 Jan 29 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101587950 Publication Model: eCollection Cited Medium: Print ISSN: 2045-452X (Print) Linking ISSN: 2045452X NLM ISO Abbreviation: Toxicol Res (Camb) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2045-452X
DOI:10.1093/toxres/tfaf188