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Polygonum barbatum extract induces ER stress-mediated UPR and autophagy to suppress colorectal cancer growth.

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Title: Polygonum barbatum extract induces ER stress-mediated UPR and autophagy to suppress colorectal cancer growth.
Authors: Chang PK; Graduate Institute of Medical Sciences, National Defense Medical University, NO. 161, Sec. 6, Minquan E. Rd., Neihu District, Taipei City 11490, Taiwan (R.O.C.).; Division of Colon and Rectal Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical University, No. 325, Sec. 2, Chenggong Rd., Neihu District, Taipei City 11490, Taiwan (R.O.C).; School of Medicine, National Defense Medical University, No. 161, Sec. 6, Minquan E. Rd., Neihu Dist., Taipei City 11490, Taiwan (R.O.C.)., Yen IC; School of Pharmacy, National Defense Medical University, No. 161, Sec. 6, Minquan E. Rd., Neihu Dist., Taipei City 11490, Taiwan (R.O.C.)., Tsai WC; Graduate Institute of Aerospace and Undersea Medicine, National Defense Medical University, No. 161, Sec. 6, Minquan E. Rd., Neihu Dist., Taipei City 11490, Taiwan (R.O.C.)., Lin KT; Department of Radiation Oncology, Cardinal Tien Hospital, No. 362, Zhongzheng Rd., Xindian Dist., New Taipei City 23148, Taiwan (R.O.C.); and School of Medicine, College of Medicine, Fu -Jen Catholic University, No. 510, Zhongzheng Rd., Xinzhuang Dist., New Taipei City 242062, Taiwan (R.O.C.)., Lee SY; Graduate Institute of Medical Sciences, National Defense Medical University, NO. 161, Sec. 6, Minquan E. Rd., Neihu District, Taipei City 11490, Taiwan (R.O.C.).; Graduate Institute of Aerospace and Undersea Medicine, National Defense Medical University, No. 161, Sec. 6, Minquan E. Rd., Neihu Dist., Taipei City 11490, Taiwan (R.O.C.).
Source: Toxicology research [Toxicol Res (Camb)] 2026 Jan 29; Vol. 15 (1), pp. tfaf188. Date of Electronic Publication: 2026 Jan 29 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101587950 Publication Model: eCollection Cited Medium: Print ISSN: 2045-452X (Print) Linking ISSN: 2045452X NLM ISO Abbreviation: Toxicol Res (Camb) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Polygonum barbatum extract induces ER stress-mediated UPR and autophagy to suppress colorectal cancer growth.
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  Data: <searchLink fieldCode="AU" term="%22Chang+PK%22">Chang PK</searchLink>; Graduate Institute of Medical Sciences, National Defense Medical University, NO. 161, Sec. 6, Minquan E. Rd., Neihu District, Taipei City 11490, Taiwan (R.O.C.).; Division of Colon and Rectal Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical University, No. 325, Sec. 2, Chenggong Rd., Neihu District, Taipei City 11490, Taiwan (R.O.C).; School of Medicine, National Defense Medical University, No. 161, Sec. 6, Minquan E. Rd., Neihu Dist., Taipei City 11490, Taiwan (R.O.C.).<br /><searchLink fieldCode="AU" term="%22Yen+IC%22">Yen IC</searchLink>; School of Pharmacy, National Defense Medical University, No. 161, Sec. 6, Minquan E. Rd., Neihu Dist., Taipei City 11490, Taiwan (R.O.C.).<br /><searchLink fieldCode="AU" term="%22Tsai+WC%22">Tsai WC</searchLink>; Graduate Institute of Aerospace and Undersea Medicine, National Defense Medical University, No. 161, Sec. 6, Minquan E. Rd., Neihu Dist., Taipei City 11490, Taiwan (R.O.C.).<br /><searchLink fieldCode="AU" term="%22Lin+KT%22">Lin KT</searchLink>; Department of Radiation Oncology, Cardinal Tien Hospital, No. 362, Zhongzheng Rd., Xindian Dist., New Taipei City 23148, Taiwan (R.O.C.); and School of Medicine, College of Medicine, Fu -Jen Catholic University, No. 510, Zhongzheng Rd., Xinzhuang Dist., New Taipei City 242062, Taiwan (R.O.C.).<br /><searchLink fieldCode="AU" term="%22Lee+SY%22">Lee SY</searchLink>; Graduate Institute of Medical Sciences, National Defense Medical University, NO. 161, Sec. 6, Minquan E. Rd., Neihu District, Taipei City 11490, Taiwan (R.O.C.).; Graduate Institute of Aerospace and Undersea Medicine, National Defense Medical University, No. 161, Sec. 6, Minquan E. Rd., Neihu Dist., Taipei City 11490, Taiwan (R.O.C.).
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  Data: <searchLink fieldCode="JN" term="%22101587950%22">Toxicology research</searchLink> [Toxicol Res (Camb)] 2026 Jan 29; Vol. 15 (1), pp. tfaf188. <i>Date of Electronic Publication: </i>2026 Jan 29 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101587950 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2045-452X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222045452X%22">2045452X </searchLink><i>NLM ISO Abbreviation: </i>Toxicol Res (Camb) <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1093/toxres/tfaf188
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      – Code: eng
        Text: English
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      – TitleFull: Polygonum barbatum extract induces ER stress-mediated UPR and autophagy to suppress colorectal cancer growth.
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              Text: 2026 Jan 29
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              Y: 2026
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