SARS-CoV-2 T-cell vaccine VB10.2210 induces broad T-cell responses in a phase 1/2 open-label clinical trial.

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Title: SARS-CoV-2 T-cell vaccine VB10.2210 induces broad T-cell responses in a phase 1/2 open-label clinical trial.
Authors: Tøndel C; Haukeland University Hospital, Department of Pediatrics and University of Bergen, Department of Clinical Science, Bergen, Norway., Jenum S; Oslo University Hospital, Department of Infectious Diseases, Oslo, Norway., Tonby K; Oslo University Hospital, Department of Infectious Diseases, Oslo, Norway; University of Oslo, Institute of Clinical Medicine, Oslo, Norway., Christensen EE; Oslo University Hospital, Department of Infectious Diseases, Oslo, Norway; University of Oslo, Institute of Clinical Medicine, Oslo, Norway., Cox RJ; University of Bergen, Department of Clinical Science, The Influenza Center, Bergen, Norway; Haukeland University Hospital, Department of Microbiology, Bergen, Norway., Onyango TB; University of Bergen, Department of Clinical Science, The Influenza Center, Bergen, Norway; Haukeland University Hospital, Department of Microbiology, Bergen, Norway., Skeie LG; Oslo University Hospital, Department of Infectious Diseases, Oslo, Norway., Robins H; Adaptive Biotechnologies, Seattle, WA, USA., Klinger M; Adaptive Biotechnologies, Seattle, WA, USA., Banbury B; Adaptive Biotechnologies, Seattle, WA, USA., Bello T; Adaptive Biotechnologies, Seattle, WA, USA., Osborne EJ; Adaptive Biotechnologies, Seattle, WA, USA., Jørgensen MJ; Nykode Therapeutics ASA, Oslo, Norway. Electronic address: Mjjorgensen@nykode.com., Pourpe S; Nykode Therapeutics ASA, Oslo, Norway., Leikfoss IS; Nykode Therapeutics ASA, Oslo, Norway., Jürgens T; Nykode Therapeutics ASA, Oslo, Norway., Wold H; Nykode Therapeutics ASA, Oslo, Norway., Torhaug S; Nykode Therapeutics ASA, Oslo, Norway., Makvandi-Nejad S; Nykode Therapeutics ASA, Oslo, Norway., Edo-Matas D; Nykode Therapeutics ASA, Oslo, Norway., Schjetne K; Nykode Therapeutics ASA, Oslo, Norway., Fredriksen AB; Nykode Therapeutics ASA, Oslo, Norway., Norheim G; Nykode Therapeutics ASA, Oslo, Norway., Dyrhol-Riise AM; Oslo University Hospital, Department of Infectious Diseases, Oslo, Norway; University of Oslo, Institute of Clinical Medicine, Oslo, Norway.
Source: Vaccine [Vaccine] 2026 Mar 07; Vol. 75, pp. 128290. Date of Electronic Publication: 2026 Feb 01.
Publication Type: Journal Article; Clinical Trial, Phase II; Clinical Trial, Phase I
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8406899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2518 (Electronic) Linking ISSN: 0264410X NLM ISO Abbreviation: Vaccine Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-2518
DOI:10.1016/j.vaccine.2026.128290