Targeting ENO1 reprograms macrophage polarization to trigger antitumor immunity and improves the therapeutic effect of radiotherapy.
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| Title: | Targeting ENO1 reprograms macrophage polarization to trigger antitumor immunity and improves the therapeutic effect of radiotherapy. |
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| Authors: | Lin YS; Department of Chest Surgery, China Medical University Hospital, Taichung, Taiwan., Chang HY; Institute of Molecular Medicine and Bioengineering, National Yang Ming Chiao Tung University, Hsinchu, Taiwan.; Center of Proton Therapy, China Medical University Hospital, China Medical University, Taichung, Taiwan., Hong WZ; Center of Proton Therapy, China Medical University Hospital, China Medical University, Taichung, Taiwan., Chen JY; Center of Proton Therapy, China Medical University Hospital, China Medical University, Taichung, Taiwan., Huang WC; HuniLife Biotechnology, Taipei City, Taiwan., Yuan TT; HuniLife Biotechnology, Taipei City, Taiwan., Ke TW; Department of Colorectal Surgery, China Medical University Hospital, China Medical University, Taichung, Taiwan.; School of Chinese Medicine, China Medical University, Taichung, Taiwan., Tsai YY; Department of Colorectal Surgery, China Medical University Hospital, China Medical University, Taichung, Taiwan.; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan., Chen TH; Department of Surgery, China Medical University Hospital, Taichung, Taiwan., Liang JA; Center of Proton Therapy, China Medical University Hospital, China Medical University, Taichung, Taiwan.; Department of Radiation Oncology, China Medical University Hospital, China Medical University, Taichung, Taiwan., Chao JI; Institute of Molecular Medicine and Bioengineering, National Yang Ming Chiao Tung University, Hsinchu, Taiwan.; Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan.; Center for Intelligent Drug Systems and Smart Bio-Devices, National Yang Ming Chiao Tung University, Hsinchu, Taiwan., Chao KSC; Center of Proton Therapy, China Medical University Hospital, China Medical University, Taichung, Taiwan.; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.; Department of Radiation Oncology, China Medical University Hospital, China Medical University, Taichung, Taiwan., Huang KC; Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung, Taiwan. flylerd0425@gmail.com.; Translation Research Core, China Medical University Hospital, China Medical University, Taichung, Taiwan. flylerd0425@gmail.com.; Cancer Biology and Precision Therapeutics Center, China Medical University, Taichung, Taiwan. flylerd0425@gmail.com.; Office of Research and Development, Asia University, Taichung, Taiwan. flylerd0425@gmail.com. |
| Source: | Cell death & disease [Cell Death Dis] 2026 Feb 02; Vol. 17 (1), pp. 194. Date of Electronic Publication: 2026 Feb 02. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-4889 |
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| DOI: | 10.1038/s41419-026-08416-7 |
