M18BP1 valency and a distributed interaction footprint determine epigenetic centromere specification in humans.

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Title: M18BP1 valency and a distributed interaction footprint determine epigenetic centromere specification in humans.
Authors: Walstein K; Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Straße 11, Dortmund, 44227, Germany.; Centre for Clinical Trials Münster, Münster, 48149, Germany., Hill L; Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Straße 11, Dortmund, 44227, Germany., Vogt D; Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Straße 11, Dortmund, 44227, Germany., Oberste-Lehn L; Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Straße 11, Dortmund, 44227, Germany., Janning P; Mass Spectrometry Facility, Max Planck Institute of Molecular Physiology, Otto-Hahn-Straße 11, Dortmund, 44227, Germany., Vetter IR; Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Straße 11, Dortmund, 44227, Germany., Pan D; Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Straße 11, Dortmund, 44227, Germany.; Research Division, Chugai Pharmaceutical Co., Ltd., Yokohama, 244-8602, Japan., Musacchio A; Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Straße 11, Dortmund, 44227, Germany. andrea.musacchio@mpi-dortmund.mpg.de.; Centre for Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen, Germany. andrea.musacchio@mpi-dortmund.mpg.de.
Source: The EMBO journal [EMBO J] 2026 Mar; Vol. 45 (5), pp. 1537-1572. Date of Electronic Publication: 2026 Feb 02.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1460-2075
DOI:10.1038/s44318-026-00698-z