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Stereoselective, sex-dependent 5-HT2A receptor modulation of cortical plasticity by MDMA in mice.

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Title: Stereoselective, sex-dependent 5-HT2A receptor modulation of cortical plasticity by MDMA in mice.
Authors: Gaines-Smith MC; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; Biomedical Sciences Graduate Program, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Silverman JM; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; Biomedical Sciences Graduate Program, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Fiorillo M; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; Biomedical Sciences Graduate Program, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Younkin J; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.; Department of Biology, Virginia State University, Petersburg, VA, USA., Moore KN; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Maltman JL; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; Biomedical Sciences Graduate Program, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., de la Fuente Revenga M; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA., Wolstenholme JT; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Glennon RA; Department of Medicinal Chemistry, Virginia Commonwealth University School of Pharmacy, Richmond, VA, USA., Dukat M; Department of Medicinal Chemistry, Virginia Commonwealth University School of Pharmacy, Richmond, VA, USA., González-Maeso J; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA. javier.maeso@vcuhealth.org.
Source: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2026 May; Vol. 51 (6), pp. 1011-1022. Date of Electronic Publication: 2026 Feb 02.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8904907 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1740-634X (Electronic) Linking ISSN: 0893133X NLM ISO Abbreviation: Neuropsychopharmacology Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Gaines-Smith+MC%22">Gaines-Smith MC</searchLink>; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; Biomedical Sciences Graduate Program, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Silverman+JM%22">Silverman JM</searchLink>; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; Biomedical Sciences Graduate Program, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Fiorillo+M%22">Fiorillo M</searchLink>; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; Biomedical Sciences Graduate Program, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Younkin+J%22">Younkin J</searchLink>; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.; Department of Biology, Virginia State University, Petersburg, VA, USA.<br /><searchLink fieldCode="AU" term="%22Moore+KN%22">Moore KN</searchLink>; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Maltman+JL%22">Maltman JL</searchLink>; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; Biomedical Sciences Graduate Program, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22de+la+Fuente+Revenga+M%22">de la Fuente Revenga M</searchLink>; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Wolstenholme+JT%22">Wolstenholme JT</searchLink>; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Glennon+RA%22">Glennon RA</searchLink>; Department of Medicinal Chemistry, Virginia Commonwealth University School of Pharmacy, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Dukat+M%22">Dukat M</searchLink>; Department of Medicinal Chemistry, Virginia Commonwealth University School of Pharmacy, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22González-Maeso+J%22">González-Maeso J</searchLink>; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA. javier.maeso@vcuhealth.org.
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