Toll signaling controls stem cell proliferation in intestinal regeneration and tumorigenesis.

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Title: Toll signaling controls stem cell proliferation in intestinal regeneration and tumorigenesis.
Authors: Peng G; The Affiliated XiangTan Central Hospital of Hunan University, School of Biomedical Sciences, Hunan University, Changsha, 410082, Hunan Province, China.; Hunan Key Laboratory of Animal Models and Molecular Medicine, Hunan University, Changsha, 410082, Hunan Province, China., Yang S; The Affiliated XiangTan Central Hospital of Hunan University, School of Biomedical Sciences, Hunan University, Changsha, 410082, Hunan Province, China.; Hunan Key Laboratory of Animal Models and Molecular Medicine, Hunan University, Changsha, 410082, Hunan Province, China., Zhang Y; The Affiliated XiangTan Central Hospital of Hunan University, School of Biomedical Sciences, Hunan University, Changsha, 410082, Hunan Province, China.; Hunan Key Laboratory of Animal Models and Molecular Medicine, Hunan University, Changsha, 410082, Hunan Province, China., Zhao Y; The Affiliated XiangTan Central Hospital of Hunan University, School of Biomedical Sciences, Hunan University, Changsha, 410082, Hunan Province, China.; Hunan Key Laboratory of Animal Models and Molecular Medicine, Hunan University, Changsha, 410082, Hunan Province, China., Huang X; Intelliphecy Center for Systems Medicine, Intelliphecy, Shenzhen, 518000, China., Yi S; Department of General Surgery, The Second Xiangya Hospital of Central South University, Changsha, 410011, Hunan, China., Gu L; Epigenetics Laboratory, Max Planck Institute for Heart and Lung Research, 61231, Bad Nauheim, Germany., Zhu G; The Affiliated XiangTan Central Hospital of Hunan University, School of Biomedical Sciences, Hunan University, Changsha, 410082, Hunan Province, China.; Hunan Key Laboratory of Animal Models and Molecular Medicine, Hunan University, Changsha, 410082, Hunan Province, China., Zheng K; The Affiliated XiangTan Central Hospital of Hunan University, School of Biomedical Sciences, Hunan University, Changsha, 410082, Hunan Province, China.; Hunan Key Laboratory of Animal Models and Molecular Medicine, Hunan University, Changsha, 410082, Hunan Province, China., Zhou H; Gastroenterology Department 1,The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, Changsha, 410013, Hunan, China. zhouhuijun@hnca.org.cn., Han K; The Affiliated XiangTan Central Hospital of Hunan University, School of Biomedical Sciences, Hunan University, Changsha, 410082, Hunan Province, China. hankang1988@hnu.edu.cn.; Hunan Key Laboratory of Animal Models and Molecular Medicine, Hunan University, Changsha, 410082, Hunan Province, China. hankang1988@hnu.edu.cn., Zhou J; The Affiliated XiangTan Central Hospital of Hunan University, School of Biomedical Sciences, Hunan University, Changsha, 410082, Hunan Province, China. junzhou82@hnu.edu.cn.; Hunan Key Laboratory of Animal Models and Molecular Medicine, Hunan University, Changsha, 410082, Hunan Province, China. junzhou82@hnu.edu.cn.
Source: EMBO reports [EMBO Rep] 2026 Mar; Vol. 27 (5), pp. 1270-1300. Date of Electronic Publication: 2026 Feb 03.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1469-3178
DOI:10.1038/s44319-026-00693-9