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Development of a chaperone-mediated protein degrader targeting ERK5 that efficaciously reduces tumor growth.

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Bibliographic Details
Title:	Development of a chaperone-mediated protein degrader targeting ERK5 that efficaciously reduces tumor growth.
Authors:	Yang X; Ranok Therapeutics (Hangzhou), Inc, Hangzhou, Zhejiang, 310018, China., Yin W; Ranok Therapeutics (Hangzhou), Inc, Hangzhou, Zhejiang, 310018, China., Xu M; Ranok Therapeutics (Hangzhou), Inc, Hangzhou, Zhejiang, 310018, China., Tusa I; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, Florence, 50134, Italy., Menconi A; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, Florence, 50134, Italy., Dai Y; Ranok Therapeutics (Hangzhou), Inc, Hangzhou, Zhejiang, 310018, China., Ding Q; Ranok Therapeutics (Hangzhou), Inc, Hangzhou, Zhejiang, 310018, China., Wang G; Ranok Therapeutics (Hangzhou), Inc, Hangzhou, Zhejiang, 310018, China., Foley KP; Ranok Therapeutics (Hangzhou), Inc, Hangzhou, Zhejiang, 310018, China., Rovida E; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, Florence, 50134, Italy. elisabetta.rovida@unifi.it., Ying W; Ranok Therapeutics (Hangzhou), Inc, Hangzhou, Zhejiang, 310018, China. wying@ranoktherapeutics.com.
Source:	Cell communication and signaling : CCS [Cell Commun Signal] 2026 Feb 03; Vol. 24 (1). Date of Electronic Publication: 2026 Feb 03.
Publication Type:	Journal Article
Journal Info:	Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X (Electronic) Linking ISSN: 1478811X NLM ISO Abbreviation: Cell Commun Signal Subsets: MEDLINE
Database:	MEDLINE Ultimate

Description
ISSN:	1478-811X
DOI:	10.1186/s12964-026-02682-w